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Use of corticosteroids in a population-based cohort of boys with duchenne and becker muscular dystrophy.

Author: , CampbellKimberly A, CiafaloniEmma, CunniffChristopher, DruschelCharlotte M, FoxDeborah J, JamesKatherine A, MathewsKatherine D, MatthewsDennis J, MeaneyF John, MillerLisa A, MillerTimothy M, PandyaShree, RomittiPaul A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Corticosteroids are increasingly used to treat Duchenne and Becker muscular dystrophy, but their use can lead to side effects such as weight gain and behavioral problems. This study reviewed the use of corticosteroids in a large cohort of boys with muscular dystrophy.
Paper Details　
Original Abstract of the Article :
The use of corticosteroids for treatment of Duchenne and Becker muscular dystrophy in clinical practice from 1991 through 2005 was reviewed in a large population-based cohort (MD STARnet) of boys in 4 regional sites and 6 clinics of the United States. Corticosteroid use increased from 20% (11 of 56 ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/20207610

データ提供：米国国立医学図書館（NLM）

Corticosteroid Use in Duchenne and Becker Muscular Dystrophy: A Population-Based Cohort Study

Duchenne and Becker muscular dystrophy (DMD/BMD) are debilitating genetic disorders affecting muscle function. This study examines the use of corticosteroids in a large population-based cohort of boys with DMD/BMD in the United States. The authors analyzed data from the MD STARnet database, revealing an increasing trend in corticosteroid use from 1991 to 2005. The study also provides information on the median age of corticosteroid initiation, dosage, and common reasons for discontinuation. This research highlights the evolving clinical practice patterns regarding corticosteroid use in DMD/BMD, offering valuable insights into current management strategies.

The Evolving Landscape of DMD/BMD Treatment

The study demonstrates a significant increase in corticosteroid use for DMD/BMD over time, reflecting advancements in understanding the benefits and risks of these medications. The findings provide a snapshot of current clinical practice patterns, highlighting the need for further research to optimize corticosteroid therapy and minimize potential side effects.

Navigating the Complexities of DMD/BMD Care

This research underscores the complexity of managing DMD/BMD, highlighting the importance of individualizing treatment approaches based on patient characteristics and response to therapy. The study provides valuable insights for healthcare professionals, informing their decision-making regarding corticosteroid use and ensuring optimal patient care.

Dr. Camel's Conclusion

The desert of DMD/BMD is a challenging landscape for patients and their families. This research provides a compass for navigating this terrain, revealing the evolving use of corticosteroids in managing these conditions. It's a reminder that the journey toward optimal care requires ongoing research, collaboration, and a commitment to improving the lives of those affected by these devastating diseases.

Date :
  1. Date Completed 2011-02-25
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

20207610

DOI: Digital Object Identifier

NIHMS954039

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Languages

English

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