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Other drugs acting on nervous system associated with QT-interval prolongation.
Author: Di GirolamoGuillermo, KellerGuillermo Alberto, PonteMarcelo L
Original Abstract of the Article :
Several drugs acting on the nervous system have been implicated in the prolongation of the QT interval. Leaving aside the antidepressant and antipsychotic drugs, some have shown to prolong the QT interval in vivo. These include opioids, particularly methadone, inhalational anesthetics, and some prep...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/157488610789869256
データ提供:米国国立医学図書館(NLM)
Navigating the Labyrinth of QT Interval Prolongation
This research takes us into the complex world of [QT interval prolongation], a cardiac condition that can increase the risk of life-threatening arrhythmias. The authors explore the potential for various drugs acting on the [nervous system] to contribute to QT interval prolongation. They delve into the mechanisms by which these drugs, including [opioids, inhalational anesthetics, and cough preparations], can affect the heart's electrical activity.
Unveiling the Hidden Dangers of QT Interval Prolongation
This review highlights the potential for a diverse range of drugs to prolong the QT interval, including [methadone], [buprenorphine], [oxycodone], [muscle relaxants], and [antineoplastic chemotherapy]. It emphasizes the importance of considering the potential for QT prolongation when prescribing these medications, particularly for individuals with [congenital long QT syndrome] or other risk factors. It's like navigating a labyrinth of drug interactions, understanding the potential for unexpected effects on the heart's rhythm.
A Desert of Cardiac Risks: Knowing the Terrain
This research serves as a reminder that even seemingly safe medications can pose cardiac risks. It underscores the importance of a comprehensive understanding of drug interactions and potential side effects. It's like navigating a vast desert, where knowing the terrain and recognizing potential dangers is essential for a safe journey.
Dr.Camel's Conclusion
This review highlights the potential for various drugs acting on the nervous system to prolong the QT interval, increasing the risk of arrhythmias. The authors emphasize the importance of considering this risk when prescribing these medications, particularly for vulnerable individuals. Further research is needed to understand the mechanisms and better predict which patients are most susceptible to QT interval prolongation.
Date :
- Date Completed 2010-06-07
- Date Revised 2022-03-16
Further Info :
Related Literature
English
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