Effects of dolasetron: A Synthesis of Findings from 27 Studies

  1. Home
  2. Effects of dolasetron
This information is not medical advice and is not a substitute for diagnosis or treatment by a physician.Data sources and disclaimers (data limitations, copyright, etc.)The analysis on "Effects of dolasetron: A Synthesis of Findings from 27 Studies" on this page is based on PubMed data provided by the U.S. National Library of Medicine (NLM). However, NLM does not endorse or verify these analyses.

This analysis is based on research papers included in PubMed, but medical research is constantly evolving and may not fully reflect the latest findings. There may also be biases towards certain research areas.

This information is not medical advice and is not a substitute for diagnosis or treatment by a physician. If you have concerns about "Effects of dolasetron: A Synthesis of Findings from 27 Studies", please consult your doctor.

For NLM copyright information, please see Link to NLM Copyright Page
PubMed data is obtained via Hugging Face Datasets: Link to DatasetPlease check the disclaimer.
This page's analysis is based on PubMed data provided by the U.S. National Library of Medicine (NLM).
Original Abstract of the Article

Main Research Findings

Dolasetron is an effective antiemetic medication used to reduce nausea and vomiting in patients undergoing chemotherapy or surgery requiring anesthesia. However, it can cause adverse cardiac events such as arrhythmia. Several studies have investigated interventions to mitigate the cardiac risks of dolasetron. For example, 26 is a systematic review and network meta-analysis of the comparative safety of 5-HT3 receptor antagonists in patients undergoing surgery, which suggests that dolasetron may have a lower cardiac risk compared to other 5-HT3 receptor antagonists. On the other hand, 3 is a case report of heart block and prolonged QTc interval following muscle relaxant reversal, suggesting that the use of multiple medications, including dolasetron, may contribute to cardiac conduction disturbances and lead to heart block or prolonged QTc interval. However, 6 is a study that investigated whether perioperative doses of ondansetron or dolasetron prolong the rate-corrected QT electrocardiographic interval (QTc) by more than 60 milliseconds or increase the proportion of patients with QTc greater than 500 milliseconds in patients undergoing noncardiac surgery, and found no significant prolongation of QTc interval with either ondansetron or dolasetron.

Taken together, these findings indicate that dolasetron is an effective medication for nausea and vomiting, but its cardiac risks cannot be completely ruled out. Caution should be exercised, especially when using it in combination with other medications or in patients with pre-existing heart conditions. It is crucial to discuss the risks and benefits of dolasetron use with your doctor.

Benefits and Risks

Benefit Summary

Dolasetron is an effective drug for reducing nausea and vomiting in patients undergoing chemotherapy or surgery requiring anesthesia. 14 states that dolasetron, when used in combination with other antiemetics, can effectively control acute vomiting and improve patients’ quality of life. Additionally, mentions that dolasetron is also effective in preventing postoperative nausea and vomiting.

Risk Summary

Dolasetron may have adverse effects on the heart. 26 suggests that dolasetron may have a lower cardiac risk compared to other 5-HT3 receptor antagonists; however, caution is still needed in patients with pre-existing heart conditions. 3 suggests that the use of multiple medications, including dolasetron, may contribute to cardiac conduction disturbances and lead to heart block or prolonged QTc interval. Also, 1 suggests that dolasetron may prolong the QTc interval.

Comparison of Studies

Similarities

These studies suggest that dolasetron is an effective drug for treating nausea and vomiting. They also suggest that dolasetron may pose cardiac risks, but the extent of the risk may vary depending on the patient's condition and the use of other medications.

Differences

These studies present conflicting conclusions regarding the cardiac risks of dolasetron. Some studies suggest that dolasetron may have a lower cardiac risk compared to other 5-HT3 receptor antagonists, while others suggest that the use of multiple medications, including dolasetron, may contribute to cardiac conduction disturbances and lead to heart block or prolonged QTc interval. Additionally, one study concluded that there is no significant prolongation of QTc interval with ondansetron or dolasetron. These discrepancies warrant further investigation.

Consistency and Contradictions

Research findings are inconsistent regarding whether dolasetron poses cardiac risks. While some studies suggest that dolasetron may have a lower cardiac risk compared to other 5-HT3 receptor antagonists, others suggest that the use of multiple medications, including dolasetron, may contribute to cardiac conduction disturbances and lead to heart block or prolonged QTc interval. These contradictions necessitate further investigation.

Real-Life Applications and Precautions

Dolasetron is an effective medication for nausea and vomiting, but its cardiac risks cannot be entirely dismissed. Caution is advised, especially when using it with other medications or in patients with pre-existing heart conditions. Consultation with a doctor is crucial to discuss the risks and benefits of dolasetron use.

Limitations of Current Research

These studies do not fully elucidate the cardiac risks associated with dolasetron. Further research is required to comprehensively explore the cardiac risks of dolasetron.

Future Research Directions

Future research should aim to delve deeper into the cardiac risks of dolasetron. Specifically, studies are needed to investigate the impact of dolasetron on cardiac conduction and the potential risks associated with its use in combination with other medications.

Conclusion

Dolasetron is an effective medication for nausea and vomiting but its cardiac risks cannot be completely ruled out. Consultation with a doctor is crucial to discuss the risks and benefits of dolasetron use. Future research is needed to investigate the cardiac risks of dolasetron more comprehensively.

Literature analysis of 27 papers
Positive Content
23
Neutral Content
0
Negative Content
4
Article Type
7
3
4
12
27
1.

Single-blind study of the effects of intravenous dolasetron mesylate versus ondansetron on electrocardiographic parameters in normal volunteers.

Author: BenedictC R, ArbogastR, MartinL, PattonL, MorrillB, HahneW

Nausea and vomiting treatment
QTc interval prolongation
Ventricular depolarization

This study examined the effects of intravenous dolasetron mesylate on electrocardiogram (ECG) intervals in healthy volunteers. Dolasetron mesylate and ondansetron both prolonged the QTc interval, but dolasetron mesylate primarily affected ventricular depolarization, while ondansetron mainly affected ventricular repolarization.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

2.

Prevention of acute emesis in cancer patients following high-dose cisplatin with the combination of oral dolasetron and dexamethasone.

Author: KrisM G, PendergrassK B, NavariR M, GroteT H, NelsonA M, ThomasV, FergusonB B, AllmanD S, PizzoB A, BakerT W, FernandoI J, ChernoffS B

Prevents acute emesis

This study evaluated the effectiveness of a combination of oral dolasetron and dexamethasone in preventing acute emesis in cancer patients receiving cisplatin.

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

4.

Lack of effect of aprepitant on hydrodolasetron pharmacokinetics in CYP2D6 extensive and poor metabolizers.

Author: LiSusie Xiujiang, PequignotEdward, PanebiancoDeborah, LupinacciPaul, MajumdarAnup, RosenLaura, AhmedTuli, RoyaltyJane E, RushmoreThomas H, MurphyM Gail, PettyKevin J

Chemotherapy-induced nausea treatment

Aprepitant, a CYP3A4 inhibitor, was found not to affect the pharmacokinetics of hydrodolasetron, the active metabolite of dolasetron, regardless of CYP2D6 metabolizer type.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

5.

Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV).

Author: SchwartzbergLee, BarbourSally Y, MorrowGary R, BallinariGianluca, ThornMichael D, CoxDavid

Reduced CINV
Side effects

Palonosetron, a 5HT3 receptor antagonist, was more effective than older drugs at preventing chemotherapy-induced nausea and vomiting.

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

6.

Perioperative doses of ondansetron or dolasetron do not lengthen the QT interval.

Author: ObalDetlef, YangDongsheng, SesslerDaniel I

QTc prolongation

This study tested the hypothesis that ondansetron or dolasetron prolongs the QTc interval more than 60 milliseconds or increases the fraction of patients with QTc greater than 500 milliseconds in patients undergoing noncardiac surgery. It also explored whether QTc prolongation is worse in diabetic patients.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

7.

Safety of an Oral Fixed Combination of Netupitant and Palonosetron (NEPA): Pooled Data From the Phase II/III Clinical Program.

Author: AaproMatti, HeskethPaul J, JordanKarin, GrallaRichard J, RossiGiorgia, RizziGiada, PalmasMarco

Safe and effective CINV prophylaxis

This analysis documented the safety profile of netupitant and palonosetron plus dexamethasone, a fixed combination therapy, in comparison with current therapies for chemotherapy-induced nausea and vomiting. The combination showed a favorable cardiac safety profile.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

8.

Coronary vasospasm leading to an acute myocardial infarction after the administration of dolasetron.

Author: AroleAdebola, KrollHenry R, BrownMorris

Treat nausea and vomiting
Cardiovascular adverse effects

This case report describes a 17-year-old adolescent girl who experienced acute myocardial infarction after receiving dolasetron for postoperative nausea and vomiting during strabismus corrective surgery. This highlights the potential for serious cardiovascular adverse effects associated with 5-hydroxytryptamine antagonists.

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

9.

[Dolasetron and shivering. A prospective randomized placebo-controlled pharmaco-economic evaluation].

Author: BockM, BauerM, RöslerL, SinnerB, MotschJ

Cost-effectiveness
Postoperative shivering prevention

Dolasetron was found to be cost-effective in preventing postoperative shivering, improving patient comfort and medical quality.

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : German

10.

Management of radiation-induced nausea and vomiting.

Author: AbdelsayedGeorge G

Reduced nausea
Reduced vomiting

5HT(3) receptor antagonists (5HT(3)RAs) are used to prevent and treat radiation-induced nausea and vomiting (RINV). 5HT(3)RAs are more effective than other antiemetics or placebo.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

11.

Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron.

Author: AdamsLaurel M, JohnsonBrendan, ZhangKe, YueLin, KirbyLyndon C, LebowitzPeter, StoltzRandall

Nausea and vomiting prevention

Casopitant is a new medication being investigated for preventing nausea and vomiting after surgery or chemotherapy. This study examined the impact of casopitant on the effectiveness of two other medications commonly used for preventing nausea and vomiting, dolasetron and granisetron.

Clinical Trial, Phase IThe first stage of clinical trials in humans. Evaluates the safety, tolerability, and pharmacokinetics of a new drug/treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

12.

Prophylaxis of postoperative vomiting in children undergoing tonsillectomy: a systematic review and meta-analysis.

Author: BoltonC M, MylesP S, NolanT, SterneJ A

Postoperative vomiting

This systematic review examines the effectiveness of various prophylactic anti-emetic interventions for preventing postoperative vomiting (POV) in children undergoing tonsillectomy. The review found strong evidence for the efficacy of dexamethasone and serotonin receptor antagonists, such as ondansetron and granisetron, in reducing POV.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

13.

Management of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

Author: FujiiYoshitaka

Effective prevention of PONV
Reduced PONV

Postoperative nausea and vomiting (PONV) is a common complication after laparoscopic cholecystectomy (LC). Propofol-based anesthesia, prophylactic antiemetics, and acupressure at the P6 point can help prevent PONV.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Retracted PublicationCases where a publication has been formally withdrawn due to the discovery of serious errors or misconduct.

Language : English

15.

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a network meta-analysis.

Author: PiechottaVanessa, AdamsAnne, HaqueMadhuri, ScheckelBenjamin, KreuzbergerNina, MonsefIna, JordanKarin, KuhrKathrin, SkoetzNicole

CINV prevention

This network meta-analysis compared the effects of antiemetic treatment combinations including neurokinin-1 (NK₁) receptor antagonists, 5-hydroxytryptamine-3 (5-HT₃) receptor antagonists, and corticosteroids on prevention of chemotherapy-induced nausea and vomiting (CINV) in adults receiving highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC).

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

16.

Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat.

Author: PetersChristopher M, HayashidaKen-ichiro, EwanEric E, NakajimaKunie, ObataHideaki, XuQinghao, YakshTony L, EisenachJames C

Chronic pain treatment

Intrathecal ondansetron, a 5-HT3 receptor antagonist, did not reduce thermal or mechanical hypersensitivity in rats with spinal nerve ligation (SNL). This suggests that descending serotonergic pathways and 5-HT3 receptor activity are not significantly involved in maintaining hypersensitivity after nerve injury.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Language : English

17.

Palonosetron for the prevention of chemotherapy-induced nausea and vomiting.

Author: Mori-VogtSherry, BlazerMarlo

CINV control

This review examines the available evidence, pharmacokinetics, safety and tolerability of palonosetron, a second-generation serotonin receptor antagonist, in the prevention of chemotherapy-induced nausea and vomiting (CINV).

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

18.

Preliminary pharmacokinetics of intravenous and subcutaneous dolasetron and pharmacodynamics of subcutaneous dolasetron in healthy cats.

Author: HerndonAndrea K, QuimbyJessica M, SiebergLiberty G, DavisLeigh, CaressAmber L, LigasSabina, HansenRyan J, WittenburgLuke A, GustafsonDanial L

Antiemetic effect

Dolasetron is a drug that is used to prevent nausea and vomiting. This study looked at the effects of giving dolasetron to cats. The study found that dolasetron did not prevent vomiting in cats, and more research is needed to determine if a higher dose would be effective.

Clinical Trial, VeterinaryClinical trials involving animals. They are conducted to evaluate the safety and efficacy of new drugs and treatments and contribute to the advancement of veterinary medicine.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

19.

Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase.

Author: DarpoB, BensonC, DotaC, FerberG, GarnettC, GreenC L, JarugulaV, JohannesenL, KeirnsJ, KrudysK, LiuJ, Ortemann-RenonC, RileyS, SarapaN, SmithB, StoltzR R, ZhouM, StockbridgeN

Early-phase clinical studies
Robust QT assessment

This study assessed whether exposure-response analysis can detect QT effects of drugs in a small study with healthy subjects. Five 'QT-positive' drugs and one negative drug were tested at two dose levels. The results indicate that robust QT assessment in early-phase clinical studies can potentially replace the thorough QT study for identifying QT effects.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Language : English

20.

Randomized comparison of two anti-emetic strategies in high-risk patients undergoing day-case gynaecological surgery.

Author: WhiteH, BlackR J, JonesM, Mar FanG C

PONV prevention

This study compared two commonly used prophylactic strategies for postoperative nausea and vomiting (PONV) in high-risk, day-case, gynaecological surgery patients.

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Language : English

21.

Pharmacological prophylaxis and management of adult postoperative/postdischarge nausea and vomiting.

Author: GolembiewskiJulie, TokumaruSheri

PONV prevention

This review discusses the management of postoperative nausea and vomiting (PONV), a common complication that can affect patient recovery. Risk factors for PONV are outlined, and effective prophylactic and treatment options are described, including the use of antiemetics and other measures to minimize risk.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

22.

A review of granisetron, 5-hydroxytryptamine3 receptor antagonists, and other antiemetics.

Author: HsuEric S

Reduced nausea
Reduced vomiting

5-HT3 receptor antagonists are recommended for the prevention and treatment of chemotherapy-induced nausea and vomiting. Other antiemetics, such as substance P/neurokinin1 receptor antagonists, and integrative medicine approaches are also being explored.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

23.

Synthesis and Development of Indole Based 5-HT3 Receptor Antagonists as Anti-Emetic Drugs in Oncology: An Update.

Author: Rivera-FonsecaJohana L, González-RivasNelly, UnnamatlaM V Basavanag, García-ElenoMarco A, ReyesHoracio, López-ValdezL Germán, Corona-BecerrilDavid, Cuevas-YañezErick

Antiemetic drug development
Reduced chemotherapy side effects

Indole-containing 5-HT3 receptor antagonists are a class of antiemetic drugs that are effective in treating nausea and vomiting caused by chemotherapy. This study discusses the synthesis, biological activities, and characteristics of these drugs, providing an overview of their development and potential for future research.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Language : English

24.

Other drugs acting on nervous system associated with QT-interval prolongation.

Author: KellerGuillermo Alberto, PonteMarcelo L, Di GirolamoGuillermo

Arrhythmias
QT prolongation
Torsades de Pointes

Several drugs, including opioids, anesthetics, and muscle relaxants, can prolong the QT interval, increasing the risk of heart rhythm abnormalities.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

25.

The utility of antiemetics in the prevention and treatment of postoperative nausea and vomiting in patients scheduled for laparoscopic cholecystectomy.

Author: FujiiYoshitaka

PONV prevention

Postoperative nausea and vomiting (PONV) is a common adverse event following laparoscopic cholecystectomy. Serotonin receptor antagonists are effective in preventing PONV, and combination antiemetic therapy is often more effective than monotherapy.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Language : English

26.

Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis.

Author: TriccoAndrea C, SoobiahCharlene, BlondalErik, VeronikiAreti A, KhanPaul A, VafaeiAfshin, IvoryJohn, StriflerLisa, AshoorHuda, MacDonaldHeather, ReynenEmily, RobsonReid, HoJoanne, NgCarmen, AntonyJesmin, MrklasKelly, HuttonBrian, HemmelgarnBrenda R, MoherDavid, StrausSharon E

Reduced nausea and vomiting
Arrhythmia

Granisetron plus dexamethasone increases the risk of arrhythmia in surgery patients.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

27.

Interventions to decrease the risk of adverse cardiac events for patients receiving chemotherapy and serotonin (5-HT3) receptor antagonists: a systematic review.

Author: TriccoAndrea C, SoobiahCharlene, HuiWing, AntonyJesmin, StruchkovVladi, HuttonBrian, HemmelgarnBrenda, MoherDavid, StrausSharon E

Nausea and vomiting treatment
Arrhythmia

This study aimed to identify interventions to mitigate the cardiac risk of 5-HT3 receptor antagonists used for nausea and vomiting.

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Language : English

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.