Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

Author: ElliottW H, ShoemakerJ D

Paper Details 
Original Abstract of the Article :
Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte Search" program provided with the VG Trio ...See full text at original site
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引用元:
https://doi.org/10.1016/0378-4347(91)80571-s

データ提供:米国国立医学図書館(NLM)

A Streamlined Approach to Urine Analysis

In the vast expanse of medical diagnostics, the analysis of urine samples provides valuable clues to the health of the body. This study presents a novel and efficient method for screening urine samples for carbohydrates, organic and amino acids. The authors, like skilled desert explorers, have developed a streamlined approach using urease treatment followed by azeotropic dehydration. This method, coupled with a sophisticated gas chromatograph-mass spectrometer, allows for rapid identification and quantification of various compounds, making it a valuable tool for diagnosing a range of genetic metabolic defects.

Fast and Accurate Diagnosis

This automated screening technique significantly reduces the time and effort required for urine analysis, providing a more efficient and accurate approach to diagnosis. The authors found that they were able to confirm diagnoses of various conditions, including cystinuria, lysinuria, and various acidurias, in a matter of minutes. This rapid and reliable diagnosis is crucial for timely intervention and treatment.

Improving Diagnostic Efficiency in the Desert of Medical Care

This research highlights the importance of continuous innovation in medical diagnostics. Just as a camel adapts to the changing desert landscape, the medical field is constantly seeking more efficient and accurate tools for diagnosis. This study is a testament to the ongoing quest for better methods for analyzing urine samples, leading to faster diagnoses and improved patient care.

Dr. Camel's Conclusion

This study is a beacon of hope in the vast desert of medical diagnostics, offering a more efficient and accurate method for analyzing urine samples. Just as a camel can navigate the desert with its keen senses and ability to conserve resources, this technology provides a powerful tool for clinicians to effectively diagnose and treat patients.

Date :
  1. Date Completed 1991-06-10
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

2026685

DOI: Digital Object Identifier

10.1016/0378-4347(91)80571-s

Related Literature

SNS
PICO Info
in preparation
Languages

English

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