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Effect of amitriptyline on symptoms in treatment naïve patients with interstitial cystitis/painful bladder syndrome.
Author: , BurksDavid A, CenLiyi, ChaiToby C, FitzGeraldMary P, FosterHarris E, HannoPhilip M, KrederKarl J, KusekJohn W, LandisJ Richard, LukaczEmily S, MayerRobert D, NickelJ Curtis, NybergLeroy M, PayneChristopher K, PetersKenneth M, PropertKathleen J, YangClaire C, YangWei
Original Abstract of the Article :
PURPOSE: Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome. The evidence to support this practice is derived mainly from a small, single site clinical trial and case reports. MATERIALS AND METHODS: We conducted a multicenter, randomized, double-b...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/20303115
データ提供:米国国立医学図書館(NLM)
Amitriptyline: A Potential Treatment for Interstitial Cystitis
This research investigates [the effectiveness of amitriptyline] in [treating interstitial cystitis/painful bladder syndrome (IC/PBS)]. The study uses a [multicenter, randomized, double-blind, placebo-controlled clinical trial] to compare [amitriptyline treatment] with [placebo] in [patients with IC/PBS]. The authors aimed to determine [the impact of amitriptyline] on [symptoms of IC/PBS] and assess [the potential benefits] of this medication.
Amitriptyline Shows Promise in Treating IC/PBS
The study found that [amitriptyline may be beneficial] for patients with IC/PBS, particularly those who [can achieve a daily dose of 50 mg or greater]. However, the researchers also found that [amitriptyline did not significantly improve symptoms] in all patients. This suggests that [amitriptyline may not be effective] for everyone with IC/PBS.
Living with Interstitial Cystitis: Finding the Right Treatment
Interstitial cystitis can be a challenging condition for patients. This research, like a camel navigating a desert of treatment options, highlights the importance of [finding the right treatment] for each individual. It underscores the need for [careful consideration] when prescribing amitriptyline for IC/PBS, and emphasizes the importance of [individualized treatment plans] that address patient-specific needs.
Dr.Camel's Conclusion
This research, like a camel searching for a reliable source of water in a dry desert, explores the potential of amitriptyline as a treatment for IC/PBS. While the findings suggest that amitriptyline may be helpful for some patients, it emphasizes the importance of personalized medicine and finding the right treatment for each individual.
Date :
- Date Completed 2010-05-06
- Date Revised 2022-03-18
Further Info :
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