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Aqueous humor concentrations of bimatoprost free acid, bimatoprost and travoprost free acid in cataract surgical patients administered multiple topical ocular doses of LUMIGAN or TRAVATAN.
Author: CravenE Randy, CurtisMichael, DahlinDavid, DubinerHarvey, FaulknerRobert, MartensKimberly, MosterMarlene, OrrSusan, PailliotetCynthia, SallKenneth, SharifNajam A, WhitsonJess T
Original Abstract of the Article :
To quantify the aqueous humor (AH) concentrations of bimatoprost (amide), travoprost (isopropyl ester), and their hydrolysis products, bimatoprost free acid (BFA) and travoprost free acid (TFA), after multiple topical ocular doses of LUMIGAN and TRAVATAN, respectively, in patients awaiting cataract ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1089/jop.2009.0098
データ提供:米国国立医学図書館(NLM)
Bimatoprost and Travoprost: A Journey Through the Desert of Ocular Pharmacology
The eye, like a delicate oasis in the vast desert of the human body, requires careful attention and precise treatment. This study investigates the aqueous humor concentrations of bimatoprost and travoprost, two commonly used prostaglandin analogs, in patients awaiting cataract surgery. The researchers, like skilled explorers, examine the pharmacokinetic properties of these drugs, providing valuable insights into their distribution and metabolism in the eye.
The study, like a well-stocked caravan, provides a detailed analysis of the aqueous humor concentrations of bimatoprost, travoprost, and their hydrolysis products following multiple topical ocular doses. This research offers a deeper understanding of the pharmacokinetic profile of these drugs, guiding clinicians towards more informed treatment strategies and ensuring optimal therapeutic outcomes.
A Desert of Insights: Implications for Ocular Pharmacology
This study provides a valuable roadmap for navigating the intricate desert of ocular pharmacology. The researchers, like skilled cartographers, have mapped the pharmacokinetic properties of bimatoprost and travoprost, providing insights into their distribution and metabolism in the eye. This research, like a shimmering oasis, offers a deeper understanding of the mechanisms of action of these drugs, paving the way for more effective and targeted treatments.
A Desert of Possibilities: Implications for Drug Development
This research opens up a desert of possibilities for future research into ocular drug delivery and development. It highlights the need for more comprehensive studies to investigate the pharmacokinetic properties of various ocular drugs. By continuing to explore the vast and often unforgiving desert of ocular pharmacology, we can develop even more effective and safe treatments for a wide range of eye conditions.
Dr.Camel's Conclusion
This study provides valuable insights into the pharmacokinetic properties of bimatoprost and travoprost, two commonly used prostaglandin analogs. It underscores the need for more comprehensive research to investigate the pharmacokinetic profiles of various ocular drugs. This research is a reminder of the need to keep exploring the vast and often unforgiving desert of ocular pharmacology, with the hope of finding more oases of knowledge to improve patient care.
Date :
- Date Completed 2010-09-07
- Date Revised 2015-11-19
Further Info :
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