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Systemic isotretinoin in the treatment of rosacea - doxycycline- and placebo-controlled, randomized clinical study.
Author: Blume-PeytaviUlrike, GollnickHarald, HauptmannPetra, MeyerKarl-Gustav, PoppGeorg, SebastianMichael, SzabóEörs Lāszlō, WillersChristoph, ZwingersThomas, von der WethRenate
Original Abstract of the Article :
BACKGROUND: Systemic isotretinoin has been known for decades to be effective in the treatment of severe forms of rosacea, but it must be used off-label because of the lack of evidence-based data. PATIENTS AND METHODS: 573 patients with rosacea subtype II and III received one of three different dosa...See full text at original site
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引用元:
https://doi.org/10.1111/j.1610-0387.2010.07345.x
データ提供:米国国立医学図書館(NLM)
Systemic Isotretinoin: A Desert Oasis for Rosacea Relief?
Rosacea, a common skin condition, is like a stubborn desert sandstorm, leaving skin red, inflamed, and uncomfortable. This study explores the effectiveness of systemic isotretinoin as a treatment for rosacea, comparing it to doxycycline and placebo. The researchers conduct a randomized, double-blind clinical trial to determine the optimal dosage and efficacy of isotretinoin.
The study's findings indicate that systemic isotretinoin, like a refreshing desert oasis, might offer a promising solution for rosacea. Isotretinoin, at a dosage of 0.3 mg/kg, demonstrated significant superiority to placebo and non-inferiority to doxycycline in reducing lesions and improving skin condition. The researchers also note that isotretinoin displayed a similar safety profile to its use in acne treatment. This suggests that isotretinoin might be a valuable alternative to oral antibiotics for treating rosacea.
Isotretinoin: A New Oasis for Rosacea Sufferers
This study provides compelling evidence for the effectiveness of systemic isotretinoin as a treatment for rosacea. It offers a new oasis of relief for those struggling with this common and often frustrating skin condition.
Rosacea: Finding Relief in the Desert
This research is a valuable step forward in understanding and treating rosacea. It suggests that isotretinoin could be a promising new weapon in the battle against this stubborn skin condition, providing a much-needed oasis of relief for those affected.
Dr.Camel's Conclusion
This study provides evidence that systemic isotretinoin is an effective and well-tolerated treatment option for rosacea. It offers a potential new oasis of relief for those suffering from this condition, providing hope for improved skin health and well-being.
Date :
- Date Completed 2010-12-02
- Date Revised 2013-11-21
Further Info :
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