New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients.

Author: Granados-PrincipalSergio, QuilesJosé L, Ramirez-TortosaCesar L, Ramirez-TortosaM Carmen, Sanchez-RoviraPedro

Paper Details 
Original Abstract of the Article :
Anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin) are currently the most effective group of anti-neoplastic drugs used in clinical practice. Of these, doxorubicin (also called adriamycin) is a key chemotherapeutic agent in cancer treatment, although its use is limited as a conse...See full text at original site
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引用元:
https://doi.org/10.1016/j.fct.2010.04.007

データ提供:米国国立医学図書館(NLM)

Protecting Against Adriamycin Toxicity: A Quest for Antioxidant Solutions

[Anthracyclines], a class of powerful [antineoplastic drugs], are widely used in [cancer treatment]. However, their use is often limited by their toxic side effects. This study focuses on [adriamycin (doxorubicin)], a key chemotherapeutic agent, exploring the molecular mechanisms underlying its toxicity and the potential of [antioxidant nutrients] to prevent these harmful effects.

The Double-Edged Sword of Adriamycin: Fighting Cancer While Minimizing Toxicity

The study highlights the molecular mechanisms responsible for both the [anti-cancer activity] and [toxicity] of adriamycin. It also explores the potential of various [antioxidant nutrients] to mitigate the toxic side effects of this drug. Imagine a camel caravan navigating through a desert with a dual purpose: delivering essential supplies while protecting its members from the harsh environment. In the same way, adriamycin seeks to destroy cancer cells while minimizing harm to healthy cells. The research explores how antioxidants can act as a protective shield against adriamycin's potential toxicity.

Harnessing the Power of Nature: A Shield Against Chemotherapy Side Effects

This research highlights the potential of natural antioxidants like [vitamin E, vitamin C, coenzyme Q, carotenoids, vitamin A, flavonoids, polyphenol, resveratrol, antioxidant from virgin olive oil, and selenium] in protecting against [adriamycin toxicity]. These antioxidants may act as a buffer against the damaging effects of chemotherapy, offering a natural way to mitigate side effects. Just like a desert plant drawing nourishment from the harsh environment, antioxidants can help protect the body from the damaging effects of chemotherapy.

Dr. Camel's Conclusion

This study underscores the importance of exploring natural solutions to mitigate the toxic side effects of chemotherapy. Antioxidant nutrients may offer a valuable tool for improving the quality of life for patients undergoing cancer treatment. As we continue to explore the desert of cancer research, harnessing the power of nature may lead to new and innovative ways to alleviate the burden of chemotherapy.
Date :
  1. Date Completed 2010-09-13
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

20385199

DOI: Digital Object Identifier

10.1016/j.fct.2010.04.007

Related Literature

SNS
PICO Info
in preparation
Languages

English

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