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New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients.
Author: Granados-PrincipalSergio, QuilesJosé L, Ramirez-TortosaCesar L, Ramirez-TortosaM Carmen, Sanchez-RoviraPedro
Original Abstract of the Article :
Anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin) are currently the most effective group of anti-neoplastic drugs used in clinical practice. Of these, doxorubicin (also called adriamycin) is a key chemotherapeutic agent in cancer treatment, although its use is limited as a conse...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.fct.2010.04.007
データ提供:米国国立医学図書館(NLM)
Protecting Against Adriamycin Toxicity: A Quest for Antioxidant Solutions
[Anthracyclines], a class of powerful [antineoplastic drugs], are widely used in [cancer treatment]. However, their use is often limited by their toxic side effects. This study focuses on [adriamycin (doxorubicin)], a key chemotherapeutic agent, exploring the molecular mechanisms underlying its toxicity and the potential of [antioxidant nutrients] to prevent these harmful effects.The Double-Edged Sword of Adriamycin: Fighting Cancer While Minimizing Toxicity
The study highlights the molecular mechanisms responsible for both the [anti-cancer activity] and [toxicity] of adriamycin. It also explores the potential of various [antioxidant nutrients] to mitigate the toxic side effects of this drug. Imagine a camel caravan navigating through a desert with a dual purpose: delivering essential supplies while protecting its members from the harsh environment. In the same way, adriamycin seeks to destroy cancer cells while minimizing harm to healthy cells. The research explores how antioxidants can act as a protective shield against adriamycin's potential toxicity.Harnessing the Power of Nature: A Shield Against Chemotherapy Side Effects
This research highlights the potential of natural antioxidants like [vitamin E, vitamin C, coenzyme Q, carotenoids, vitamin A, flavonoids, polyphenol, resveratrol, antioxidant from virgin olive oil, and selenium] in protecting against [adriamycin toxicity]. These antioxidants may act as a buffer against the damaging effects of chemotherapy, offering a natural way to mitigate side effects. Just like a desert plant drawing nourishment from the harsh environment, antioxidants can help protect the body from the damaging effects of chemotherapy.Dr. Camel's Conclusion
This study underscores the importance of exploring natural solutions to mitigate the toxic side effects of chemotherapy. Antioxidant nutrients may offer a valuable tool for improving the quality of life for patients undergoing cancer treatment. As we continue to explore the desert of cancer research, harnessing the power of nature may lead to new and innovative ways to alleviate the burden of chemotherapy.Date :
- Date Completed 2010-09-13
- Date Revised 2022-03-16
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