CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on.

Author: WestbyMike, van der RystElna

Paper Details 
Original Abstract of the Article :
The chemokine coreceptor 5 (CCR5) antagonists are antiretroviral agents with an extracellular, host-targeted mechanism of action against HIV. Maraviroc, the first-in-class CCR5 antagonist, received regulatory approval in 2007, becoming the first oral antiretroviral from a new class in more than 10 y...See full text at original site
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引用元:
https://doi.org/10.3851/IMP1507

データ提供:米国国立医学図書館(NLM)

CCR5 Antagonists: A New Frontier in HIV Treatment

The field of [HIV treatment] is constantly seeking new and innovative strategies to combat the virus. This study reviews the progress made in the development of [CCR5 antagonists], a new class of [host-targeted antiviral agents] that block the entry of [HIV] into [host cells]. The authors provide a comprehensive overview of the clinical data available on [CCR5 antagonists], highlighting the promise of this new approach to [HIV treatment].

CCR5 Antagonists: A New Avenue for HIV Treatment

The study highlights the potential of [CCR5 antagonists] as a valuable addition to the [HIV treatment] arsenal. The authors discuss the [mechanism of action] of these agents, their [clinical efficacy], and their [safety profile]. The study also emphasizes the importance of [genotypic testing] to identify patients who are most likely to benefit from [CCR5 antagonist] therapy. These insights underscore the significant role that [CCR5 antagonists] could play in the ongoing fight against HIV.

Navigating the Desert of HIV: A New Path to Treatment

This research, like a new path emerging in the vast desert of HIV, offers a glimmer of hope for patients seeking effective treatment options. The development of CCR5 antagonists, with their unique mechanism of action and promising clinical data, presents a new frontier in the fight against HIV. These agents hold the potential to offer a more targeted and effective approach to treatment, offering a new beacon of hope in the desert of HIV infection.

Dr.Camel's Conclusion

The desert of HIV treatment is vast and complex, but new paths are constantly emerging. CCR5 antagonists represent a promising new frontier, targeting the host rather than the virus directly. These agents offer a targeted and effective approach to treatment, providing a new beacon of hope for those navigating the challenges of HIV infection.

Date :
  1. Date Completed 2010-07-15
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

20413825

DOI: Digital Object Identifier

10.3851/IMP1507

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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