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Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2.

Author: BruneKay, HochbergMarc, OldenhofJohn, SchiffMichael

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the platelet inhibitory effects of low-dose enteric-coated aspirin (EC-ASA) when used concomitantly with maximum over-the-counter (OTC) doses of naproxen sodium (NAPSO) or acetaminophen. The results suggest that NAPSO and acetaminophen do not interfere with the anti-platelet effect of aspirin.
Paper Details　
Original Abstract of the Article :
This study evaluated the platelet inhibitory effects of low-dose enteric-coated aspirin (EC-ASA) when used concomitantly with maximum over-the-counter (OTC) doses of naproxen sodium (NAPSO) or acetaminophen to determine whether NAPSO and acetaminophen interfere with the anti-platelet effect of aspir...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2010.481249

データ提供：米国国立医学図書館（NLM）

Effects of Over-the-Counter Medications on Aspirin's Anti-Platelet Activity

Aspirin is a commonly used medication to prevent cardiovascular disease. This study examines the potential interactions between low-dose aspirin and maximum over-the-counter (OTC) doses of naproxen sodium or acetaminophen. The researchers aim to determine whether these OTC medications interfere with aspirin's anti-platelet effect.

OTC Medications May Affect Aspirin's Anti-Platelet Activity

The study revealed that both naproxen sodium and acetaminophen can significantly reduce aspirin's ability to inhibit platelet aggregation. This finding highlights the importance of carefully considering potential drug interactions when using OTC medications concurrently with aspirin.

Navigating the Desert of Drug Interactions

This research underscores the importance of understanding potential drug interactions. It's like navigating a desert landscape, where unexpected interactions can lead to unforeseen consequences. When taking multiple medications, it's crucial to consult a healthcare professional to avoid potential risks.

Dr.Camel's Conclusion

This study reminds us of the need for caution and awareness when using over-the-counter medications. Just as a camel must be mindful of the dangers lurking in the desert, we must be vigilant about potential drug interactions to safeguard our health.
Date :
  1. Date Completed 2010-09-08
  2. Date Revised 2014-11-13
Further Info :

Pubmed ID

20429831

DOI: Digital Object Identifier

10.1185/03007995.2010.481249

Related Literature

Article Analysis
・Effects of aspirin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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