Mucosal bridge and pitting of the true vocal fold: an unusual complication of cidofovir injection.

Author: ManLi-Xing, RosenClark A, StathamMelissa M

Paper Details 
Original Abstract of the Article :
We describe a unique complication of intralaryngeal cidofovir injection and present the case of a patient with recurrent respiratory papillomatosis in whom both a mucosal bridge and a pit of the true vocal fold developed after intralaryngeal cidofovir injection. A 40-year-old man presented with lary...See full text at original site
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引用元:
https://doi.org/10.1177/000348941011900405

データ提供:米国国立医学図書館(NLM)

Cidofovir: A Double-Edged Sword for Laryngeal Papillomatosis

The human body is a wondrous, complex structure, and even seemingly minor interventions can sometimes have unforeseen consequences. This case report explores the potential complications of cidofovir injection, a treatment used for recurrent respiratory papillomatosis. The researchers present the case of a patient who developed a mucosal bridge and a pit on his vocal fold after receiving multiple high-dose cidofovir injections. The findings highlight the importance of carefully considering the potential risks and benefits of this treatment approach.

Unforeseen Complications of Cidofovir

The development of a mucosal bridge and pit on the vocal fold is an unusual complication of cidofovir injection, suggesting that repeated high-dose injections may lead to significant morphological changes in the vocal fold. The study underscores the need for vigilance and careful monitoring of patients receiving cidofovir therapy.

Balancing Benefits and Risks

This case report serves as a reminder that even seemingly effective treatments can have unexpected consequences. It highlights the importance of weighing the potential benefits of cidofovir therapy against the risks, particularly in cases of repeated high-dose injections. A thorough understanding of the potential complications associated with cidofovir is crucial for informing treatment decisions and ensuring patient safety.

Dr.Camel's Conclusion

This case report reveals the potential for unexpected complications associated with high-dose cidofovir injections for recurrent respiratory papillomatosis. The development of a mucosal bridge and pit on the vocal fold underscores the need for caution and careful monitoring when using this treatment approach. This case report highlights the delicate balance between therapeutic benefits and potential risks, emphasizing the importance of individualizing treatment strategies and remaining vigilant in identifying and managing potential complications.

Date :
  1. Date Completed 2010-05-18
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20433022

DOI: Digital Object Identifier

10.1177/000348941011900405

Related Literature

SNS
PICO Info
in preparation
Languages

English

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