A randomized, double-blind, placebo-controlled trial of olanzapine in the treatment of trichotillomania.

Author: BennettMark, ManciniCatherine, OakmanJonathan, PattersonBeth, Van AmeringenMichael

Paper Details 
Original Abstract of the Article :
BACKGROUND: Trichotillomania has been considered as part of the obsessive-compulsive disorder spectrum; however, trichotillomania treatment with obsessive-compulsive disorder medications has largely been unsuccessful. OBJECTIVE: To determine whether a dopaminergic treatment as used in tics and Tour...See full text at original site
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引用元:
https://doi.org/10.4088/JCP.09m05114gre

データ提供:米国国立医学図書館(NLM)

Trichotillomania: Taming the Hair-Pulling Beast with Olanzapine

Trichotillomania, a disorder characterized by the urge to pull out one's hair, is a complex beast that can wreak havoc on a person's life. While it's often associated with obsessive-compulsive disorders, the effectiveness of traditional treatments for obsessive-compulsive disorders hasn't been consistent in addressing trichotillomania. This study, like a determined explorer venturing into uncharted territory, investigated the use of olanzapine, a dopaminergic medication, as a potential treatment for trichotillomania. The researchers conducted a 12-week, randomized, double-blind, placebo-controlled trial with 25 participants, carefully monitoring their responses to olanzapine. Their findings showed that olanzapine was significantly more effective than placebo in reducing hair-pulling behaviors. The researchers observed a substantial improvement in the participants' condition using the Yale-Brown Obsessive Compulsive Scale for Trichotillomania (TTM-YBOCS) and the Clinical Global Impressions-Severity of Illness (CGI-S) scale.

Olanzapine: A Potential Weapon Against the Hair-Pulling Beast

This research suggests that olanzapine could be a safe and effective treatment option for trichotillomania. The results showed that olanzapine significantly improved the condition of participants compared to placebo, offering hope for those struggling with this disorder. It's important to note that this study involved a relatively small sample size and further research is needed to confirm these findings. The effectiveness of olanzapine was evident in the reduction of hair-pulling behaviors and the overall improvement in the participants' condition. The study suggests that olanzapine might provide relief for those who have been battling the hair-pulling beast for years.

Living with Trichotillomania: Finding Peace in the Storm

This research provides a glimmer of hope for those struggling with trichotillomania. While olanzapine shows promise as a potential treatment, it's important to remember that this is just one piece of the puzzle. Individuals with trichotillomania should consult with a mental health professional to create a personalized treatment plan that may involve therapy, medication, or a combination of both. It's a journey through a storm of hair-pulling urges, but with the right tools and support, a person can find peace and regain control of their life.

Dr. Camel's Conclusion

This study sheds light on the potential of olanzapine as a treatment for trichotillomania. While more research is necessary to fully understand its efficacy and long-term effects, the findings offer hope for those seeking relief from this challenging disorder. It's a reminder that even in the most difficult of conditions, there is hope and potential for healing.

Date :
  1. Date Completed 2011-02-16
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

20441724

DOI: Digital Object Identifier

10.4088/JCP.09m05114gre

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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