Paper Details

  1. Home
  2. Paper Details

Bisphosphonates in the treatment of metabolic bone diseases.

Author: ArantesHenrique Pierotti, Lazaretti-CastroMarise, SilvaAndré Gonçalves da

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Osteoporosis is a bone disease characterized by low bone mass and microarchitectural deterioration, increasing fracture risk. Bisphosphonates are medications that reduce bone resorption by osteoclasts, improving the balance between resorption and formation. These medications are approved for both prevention and treatment of osteoporosis and can be administered orally or intravenously. Bisphosphonates are generally well-tolerated and safe with proper administration. Serious side effects, such as osteonecrosis of the jaw, are rare. Bisphosphonates are widely prescribed for osteoporosis management.
Paper Details　
Original Abstract of the Article :
Osteoporosis is a disease characterized by low bone mass associated with the deterioration of microarchitecture, due to an imbalance either in high bone resorption or low bone formation or in both, leading to a high risk of fractures. Bisphosphonates are medications which reduce the ability of osteo...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1590/s0004-27302010000200017

データ提供：米国国立医学図書館（NLM）

Bisphosphonates in the Treatment of Metabolic Bone Diseases

Bones, the foundation of our body, can sometimes weaken, leading to conditions like osteoporosis. This study explores the role of bisphosphonates, a class of drugs that inhibit bone resorption, in the management of metabolic bone diseases, a group of disorders affecting bone health.

Strengthening the Foundation of Bone Health

The researchers examined the mechanisms of action of bisphosphonates, focusing on their ability to reduce bone resorption by osteoclasts, cells responsible for breaking down bone. This is like adding a layer of reinforcement to a crumbling foundation, ensuring the stability of our skeletal structure. The study highlights the effectiveness of bisphosphonates in preventing and treating osteoporosis, a prevalent condition that can lead to fractures.

Protecting the Foundation of Our Bodies

The research emphasizes the safety profile of bisphosphonates, suggesting that they are well-tolerated and have a favorable safety record when used appropriately. This is like building a sturdy foundation with materials that withstand the test of time, ensuring the stability and longevity of our skeletal system. The study provides valuable information for clinicians and patients seeking to manage metabolic bone diseases.

Dr.Camel's Conclusion

This study sheds light on the effectiveness and safety of bisphosphonates in managing metabolic bone diseases. It's a reminder that the foundation of our health, like the structure of a desert oasis, requires attention and care to maintain its strength and resilience.
Date :
  1. Date Completed 2011-05-04
  2. Date Revised 2019-09-17
Further Info :

Pubmed ID

20485910

DOI: Digital Object Identifier

10.1590/s0004-27302010000200017

Related Literature

Article Analysis
・Effective treatment of bone diseases
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.