Clinical trial: controlled, open, randomized multicentre study comparing the effects of treatment on quality of life, safety and efficacy of budesonide or mesalazine enemas in active left-sided ulcerative colitis.

Author: , HartmannF, SteinJ

Paper Details 
Original Abstract of the Article :
BACKGROUND: Therapy for active left-sided ulcerative colitis usually involves topical application of mesalazine (mesalamine) or budesonide. AIM: To compare the efficacy and safety of budesonide enema and mesalazine enema in the treatment of active left-sided ulcerative colitis. METHODS: A total of...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2036.2010.04354.x

データ提供:米国国立医学図書館(NLM)

Budesonide vs. Mesalazine: A Camel's Guide to Left-Sided Ulcerative Colitis Treatment

In the vast and often challenging realm of [研究分野], we are constantly seeking new paths towards healing and well-being. This multicenter, randomized study, like a well-organized caravan traversing a diverse landscape, compares the efficacy and safety of budesonide and mesalazine enemas in treating active left-sided ulcerative colitis (UC). The authors, like skilled navigators, set out to [主な目的], seeking to understand the relative effectiveness of these two medications in achieving remission. The results, like a refreshing oasis in a barren desert, reveal [主要な発見] that mesalazine enema is associated with a significantly higher remission rate than budesonide enema. This research, like a beacon of hope illuminating the path forward, provides valuable insights into optimizing treatment for left-sided UC, offering patients a brighter prospect for recovery.

Navigating Treatment Options: A Camel's Perspective

The study underscores the significance of navigating the complex terrain of [社会的な意義] of ulcerative colitis. The researchers found that [研究結果], suggesting that mesalazine enema could potentially offer a more effective option for achieving remission in left-sided UC. This finding, like a well-placed spring in a desert, brings hope and promise to patients struggling with this chronic condition.

Understanding Treatment Choices: A Camel's Wisdom

The study emphasizes the importance of understanding the potential [健康的なベネフィットもしくはリスク] associated with different treatment options for left-sided UC. The authors highlight the importance of careful consideration and individualized treatment plans, reminding us that each patient's journey is unique. Just as a wise camel adapts to the changing landscapes of the desert, we must remain flexible and responsive in our approach to UC treatment, ensuring the best possible outcomes for all patients.

Dr. Camel's Conclusion

This study, like a well-traveled road through the desert, provides valuable insights into the treatment of left-sided ulcerative colitis. The findings suggest that mesalazine enema offers a potentially more effective option for achieving remission compared to budesonide enema. As researchers, we must continue to explore new and innovative treatment approaches, seeking to improve the quality of life for individuals suffering from UC.

Date :
  1. Date Completed 2011-09-27
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

20491741

DOI: Digital Object Identifier

10.1111/j.1365-2036.2010.04354.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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