Paper Details 
Original Abstract of the Article :
Sjögren's syndrome (SS) is an autoimmune disorder whose main symptoms include xerostomia and dry eyes. It has been demonstrated that abnormal expression of aquaporin (AQP)-5 in the parotid and submandibular glands in SS model mice was corrected by cevimeline. In the present study, we orally administ...See full text at original site
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引用元:
https://doi.org/10.2739/kurumemedj.56.39

データ提供:米国国立医学図書館(NLM)

Cevimeline: A Potential Oasis for Sjögren's Syndrome

Sjögren’s syndrome (SS), a chronic autoimmune disorder, can feel like traversing a dry and desolate desert, causing debilitating dryness of the mouth and eyes. Researchers are constantly searching for new ways to alleviate these symptoms and improve the quality of life for those affected by SS.

This study, like a group of explorers searching for a source of water in the desert, investigated the potential of cevimeline, a medication used to stimulate saliva production, to improve salivary gland function in mice with SS. Their findings revealed that cevimeline, like a refreshing oasis in the desert, could potentially improve salivary gland function in SS. They observed that cevimeline normalized the expression of aquaporin-5, a protein involved in water transport, and enhanced salivary gland secretion. This research offers a glimmer of hope for those seeking relief from the dryness and discomfort associated with SS.

A Glimmer of Hope: Cevimeline for Sjögren's Syndrome

This study suggests that cevimeline could offer a potential solution for improving salivary gland function in SS. The researchers’ findings highlight the importance of understanding the role of aquaporin-5 in salivary gland function and exploring strategies to restore its expression in SS.

Finding Relief in the Desert: Managing Sjögren's Syndrome

This research offers a ray of hope for those suffering from the debilitating dryness associated with SS. The researchers’ findings suggest that cevimeline could potentially alleviate these symptoms, improving the quality of life for those affected by this challenging condition. Further research is needed to investigate the long-term effects of cevimeline and to develop more effective treatments for SS.

Dr.Camel's Conclusion

This study highlights the potential of cevimeline to improve salivary gland function in SS. The researchers’ findings offer a glimmer of hope for those seeking relief from the dryness and discomfort associated with this chronic autoimmune disorder.

Date :
  1. Date Completed 2010-09-01
  2. Date Revised 2019-09-23
Further Info :

Pubmed ID

20505281

DOI: Digital Object Identifier

10.2739/kurumemedj.56.39

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Languages

English

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