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[The amnesic effects of midazolam in premedication of children].

Author: DubostJ, KalfonF, RocheC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Intramuscular midazolam administration as premedication in children aged 4 to 10 years was found to be well-tolerated, with excellent anterograde amnesia observed. However, anxiolytic effects could not be determined due to the short interval between premedication and induction.
Paper Details　
Original Abstract of the Article :
The aim of this study was to check local and general tolerance as well as anxiolytic and amnesic effects of midazolam intramuscular administration as a premedication in 4 to 10 years old children. A double blind, comparative study with a placebo was achieved, after drawing lots, in 40 children divid...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2054701

データ提供：米国国立医学図書館（NLM）

Midazolam: A Premedication for Children with Amnesic Effects

Premedication plays a crucial role in preparing children for medical procedures, aiming to minimize anxiety and discomfort. This study investigates the effectiveness of midazolam, a benzodiazepine, as a premedication for children undergoing medical procedures. The researchers conducted a double-blind, comparative study with a placebo, comparing the local and general tolerance, anxiolytic effects, and amnesic effects of midazolam administered intramuscularly to children aged 4 to 10 years. The study found that midazolam provided excellent anterograde amnesia, demonstrating its potential as an effective premedication for children undergoing medical procedures.

Midazolam: A Promising Premedication for Children

This study highlights the potential of midazolam as a premedication for children, offering effective anterograde amnesia. The study found that midazolam was well-tolerated by children and effectively reduced their memory of the procedure. This finding suggests that midazolam can be a valuable tool in minimizing anxiety and discomfort associated with medical procedures in children.

Preparing Children for Procedures: Minimizing Anxiety and Discomfort

Medical procedures can be daunting for children. This study suggests that midazolam can play a vital role in preparing children for procedures, minimizing anxiety and discomfort. The study's findings emphasize the importance of appropriate premedication in providing a positive and less stressful experience for children undergoing medical procedures. As a wise camel navigating the vast desert, I encourage parents and healthcare professionals to prioritize the well-being of children during medical procedures.

Dr.Camel's Conclusion

Midazolam shows promise as a premedication for children, providing effective anterograde amnesia and minimizing anxiety and discomfort. As a wise camel traversing the vast desert, I encourage healthcare professionals to consider midazolam as a valuable tool for managing anxiety and discomfort in children undergoing medical procedures.

Date :
  1. Date Completed 1991-07-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2054701

DOI: Digital Object Identifier

2054701

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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