Intranasal sumatriptan powder delivered by a novel breath-actuated bi-directional device for the acute treatment of migraine: A randomised, placebo-controlled study.

Author: , DjupeslandP G, DocekalP

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Intranasal sumatriptan is an option for the treatment of migraine; however, nasal delivery using conventional spray pumps is suboptimal. METHODS: Adult subjects (n = 117) with migraine were enrolled in a multicentre, randomised, double-blind, parallel group, placebo-controlled study. ...See full text at original site
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引用元:
https://doi.org/10.1177/0333102409359314

データ提供:米国国立医学図書館(NLM)

A Breath of Relief: Intranasal Sumatriptan Powder for Migraine

The world of [migraine] is often a world of pain and discomfort, with patients seeking effective and convenient ways to manage their symptoms. This research, delving into the realm of [migraine treatment], explores the efficacy and safety of [intranasal sumatriptan powder] delivered via a [novel breath-actuated bi-directional device]. The study, conducted in a [multicenter, randomized, double-blind, placebo-controlled setting], aimed to assess the effectiveness of this new delivery method in providing pain relief during migraine attacks.

A New Approach: The Promise of Intranasal Sumatriptan Powder

The study's findings are promising, demonstrating the effectiveness of [intranasal sumatriptan powder] in providing pain relief. A significantly greater proportion of patients receiving the [10 mg or 20 mg sumatriptan powder] achieved [pain-free status] at [120 minutes] compared to those receiving [placebo]. The benefits were observed as early as [60 minutes] and sustained for up to [48 hours]. The therapy was also well-tolerated, with [metallic taste] being the most common adverse event.

A Breath of Fresh Air: Improving Migraine Management

This research suggests that [intranasal sumatriptan powder] delivered via the [novel breath-actuated device] offers a promising new approach for [migraine management]. This method appears to be both effective and well-tolerated, potentially offering a more convenient and user-friendly option for patients. As Dr. Camel, I believe that this innovation holds great promise for improving the lives of those struggling with [migraine], offering a glimmer of hope amidst the desert of pain.

Dr.Camel's Conclusion

This research offers a refreshing approach to [migraine management], showcasing the potential of [intranasal sumatriptan powder] delivered via a user-friendly device. The study's findings provide evidence for the effectiveness and safety of this innovative treatment, potentially offering a more convenient and effective option for patients. Just as a camel traverses the desert, we must continue to explore and refine our understanding of [migraine] to develop more effective and patient-centered treatment approaches.

Date :
  1. Date Completed 2010-11-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

20656704

DOI: Digital Object Identifier

10.1177/0333102409359314

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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