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Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes.

Author: GensiniGian Franco, HansonMary E, Le GrazieCristina, RotellaCarlo M, ZaninelliAugusto

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Treatment guidelines prioritize lowering LDL cholesterol (bad cholesterol) for people with high cholesterol. When statins alone aren't enough, combining them with other cholesterol-lowering medications is recommended. This study aims to identify factors that influence the success of achieving cholesterol goals, whether related to the treatment itself or patient characteristics.
Paper Details　
Original Abstract of the Article :
Treatment guidelines recommend LDL-C as the primary target of therapy in patients with hypercholesterolemia. Moreover, combination therapies with lipid-lowering drugs that have different mechanisms of action are recommended when it is not possible to attain LDL-C targets with statin monotherapy. Und...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918617/

データ提供：米国国立医学図書館（NLM）

Ezetimibe/Simvastatin vs Simvastatin: Navigating the Sands of Cholesterol Management

High cholesterol is a major risk factor for cardiovascular disease, and effective treatment is crucial for preventing heart problems. This study compares the effectiveness of ezetimibe/simvastatin combination therapy to simvastatin monotherapy in patients with coronary heart disease, investigating the most effective approach for achieving optimal cholesterol control. Imagine this as a desert traveler seeking the best path to reach a distant oasis, where the goal is to achieve optimal health.

Finding the Right Path: Optimizing Cholesterol Management

This study explores the effectiveness of different cholesterol-lowering strategies in patients with coronary heart disease. This is like a desert traveler comparing different routes, seeking the one that leads to the most efficient and effective outcome. The study suggests that ezetimibe/simvastatin combination therapy may be more effective than simvastatin monotherapy in achieving target LDL-C levels, highlighting the potential of combination therapy for optimal cholesterol management.

A Journey of Heart Health: Navigating Cholesterol Control

This research emphasizes the importance of tailoring treatment strategies to individual patient needs. This is like a desert traveler adapting their route to the changing landscape, seeking the best way to achieve their goal. By understanding the nuances of cholesterol management, healthcare professionals can provide personalized treatment plans that improve cardiovascular health and reduce the risk of heart disease.

Dr. Camel's Conclusion

This study offers valuable insights into the effectiveness of different cholesterol-lowering strategies for patients with coronary heart disease. The research suggests that ezetimibe/simvastatin combination therapy may be a more effective approach for achieving target LDL-C levels. This knowledge empowers healthcare professionals to make informed decisions about cholesterol management and guide patients on their journey toward optimal cardiovascular health.
Date :
  1. Date Completed 2010-11-29
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20663203

DOI: Digital Object Identifier

PMC2918617

Related Literature

Article Analysis
・Effective treatment of cholesterol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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