Comparison of tretinoin 0.05% cream and 3% alcohol-based salicylic acid preparation in the treatment of acne vulgaris.

Author: AkarsuS, BabayevaL, FetilE, GüneşA T

Paper Details 
Original Abstract of the Article :
BACKGROUND: No single effective topical treatment is available for treating all pathogenic factors causing acne vulgaris (AV). Salicylic acid (SA), tretinoin (all-TRA) and clindamycin phosphate (CDP) are known to to be effective agents depending on their comedolytic and anti-inflammatory properties....See full text at original site
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引用元:
https://doi.org/10.1111/j.1468-3083.2010.03793.x

データ提供:米国国立医学図書館(NLM)

Acne Vulgaris: A Comparative Study of Topical Treatments

This study compares the effectiveness and tolerability of two topical treatments for acne vulgaris: a combination of salicylic acid (SA) and clindamycin phosphate (CDP) and a combination of tretinoin (all-TRA) and CDP. The authors conducted a 12-week, randomized clinical trial involving patients with mild to moderate facial acne. They assessed the efficacy of each treatment by measuring lesion counts, global improvement, quality of life, and skin barrier function. Their findings highlight the effectiveness of both treatments in reducing acne lesions and improving overall skin quality.

Tackling Acne with Topical Treatments

The study demonstrates that both SA+CDP and all-TRA+CDP are effective in reducing acne lesions and improving overall skin quality. The authors found that both treatments were well-tolerated, with minimal side effects. While both treatments showed comparable efficacy, all-TRA+CDP exhibited faster reductions in total lesion counts in the early stages of treatment. This information can guide physicians in selecting the most suitable treatment for individual patients based on their needs and preferences.

Choosing the Right Treatment

Acne can be a frustrating and sometimes painful condition, impacting self-esteem and social confidence. The study provides encouraging news for individuals seeking effective topical treatments. Both SA+CDP and all-TRA+CDP have been shown to be effective in reducing acne lesions and improving skin quality. It’s crucial to consult with a dermatologist to determine the best treatment approach for your specific needs and to address any concerns you may have.

Dr.Camel's Conclusion

This study underscores the importance of personalized treatment approaches for acne vulgaris. The authors demonstrate that both SA+CDP and all-TRA+CDP are effective and well-tolerated treatment options. The findings provide valuable insights for physicians in selecting the most suitable treatment for individual patients based on their specific needs. Remember, choosing the right treatment for acne can be a collaborative process between you and your dermatologist. Open communication is key to ensuring a successful treatment journey.

Date :
  1. Date Completed 2011-05-26
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

20666879

DOI: Digital Object Identifier

10.1111/j.1468-3083.2010.03793.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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