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A comparative study of naproxen sodium, pizotyline and placebo in migraine prophylaxis.

Author: BellavanceA J, MelocheJ P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 176 migraine patients found that both naproxen sodium and pizotyline were more effective than placebo in preventing migraine attacks.
Paper Details　
Original Abstract of the Article :
318 patients satisfying the Ad Hoc Committee's criteria for common or classical migraine were entered into an 8 week single-blind placebo recording phase to establish, by diary cards, the frequency and severity of their attacks. 176 patients completed this and had records indicating 4-8 episodes in ...See full text at original site
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引用元：
https://doi.org/10.1111/j.1526-4610.1990.hed3011710.x

データ提供：米国国立医学図書館（NLM）

Naproxen Sodium and Pizotyline: Oases in the Desert of Migraine Prophylaxis

Migraine, a debilitating neurological disorder characterized by severe headaches, can significantly impact an individual's quality of life. This research investigates the efficacy of two medications, naproxen sodium and pizotyline, as prophylactic treatments for migraine. The study, conducted in a single-blind placebo-controlled setting, evaluated the effectiveness of these medications in reducing the frequency and severity of migraine attacks, much like seeking a reliable source of water in the vast desert of migraine treatment. The results revealed that both naproxen sodium and pizotyline were more effective than placebo in preventing migraine attacks, offering a glimmer of hope for individuals struggling with this condition.

Finding Relief in the Desert of Migraine

The study's findings offer a potential oasis of relief for individuals with migraine. The effectiveness of both naproxen sodium and pizotyline in reducing the frequency and severity of migraine attacks suggests that these medications could play a significant role in improving the quality of life for those affected by this condition. This is akin to discovering a hidden spring in the desert, providing a source of sustenance and respite from the relentless onslaught of migraine headaches.

Navigating the Desert of Migraine Treatment

This study emphasizes the need for individualized treatment approaches in migraine management. Just as a camel chooses the most suitable path through the desert, healthcare professionals must carefully consider a patient's individual characteristics and preferences when selecting a treatment plan. This study serves as a reminder that there is no one-size-fits-all approach to managing migraine, and finding the right solution may involve exploring various treatment options.

Dr.Camel's Conclusion

Naproxen sodium and pizotyline emerge as potential oases in the desert of migraine prophylaxis, offering hope for individuals struggling with this debilitating condition. This study highlights the importance of individualized treatment approaches and underscores the ongoing quest for effective migraine management.

Date :
  1. Date Completed 1991-04-18
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2074163

DOI: Digital Object Identifier

10.1111/j.1526-4610.1990.hed3011710.x

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・Effective treatment of migraine
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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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