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Economic analysis of cinacalcet in combination with low-dose vitamin D versus flexible-dose vitamin D in treating secondary hyperparathyroidism in hemodialysis patients.

Author: AlmehmiAmmar, LuJohn, PregenzerMark, QuarlesL Darryl, ShiremanTheresa I, WetmoreJames B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The ACHIEVE trial compared the effectiveness of cinacalcet plus low-dose vitamin D to vitamin D alone in treating secondary hyperparathyroidism (SHPT). This study examines the cost implications of these treatment approaches.
Paper Details　
Original Abstract of the Article :
The ACHIEVE (Optimizing the Treatment of Secondary Hyperparathyroidism: A Comparison of Sensipar and Low Dose Vitamin D vs Escalating Doses of Vitamin D Alone) trial evaluated the efficacy of treatment with cinacalcet plus low-dose activated vitamin D analogues (Cinacalcet-D) compared with vitamin D...See full text at original site
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引用元：
https://doi.org/10.1053/j.ajkd.2010.07.012

データ提供：米国国立医学図書館（NLM）

Economic Analysis of Cinacalcet vs. Vitamin D for Secondary Hyperparathyroidism

The field of nephrology, a desert of complex challenges, seeks to find effective and cost-effective treatments for chronic kidney disease. This study examines the economic implications of two treatment regimens for secondary hyperparathyroidism, a common complication of chronic kidney disease. Researchers, like astute desert traders, carefully weighed the costs and benefits of cinacalcet in combination with low-dose vitamin D versus flexible-dose vitamin D alone. Their analysis reveals that cinacalcet, a novel therapeutic agent, offers a cost-effective option for achieving desired treatment targets.

Cost-Effectiveness of Cinacalcet

The study demonstrated that cinacalcet, a promising oasis in the desert of cost-effective therapies, offers a favorable economic profile compared to vitamin D alone, achieving comparable efficacy at a lower cost. This finding is crucial for healthcare systems seeking to optimize resource allocation.

Optimizing Treatment Choices

This research provides valuable insights into the economic aspects of treating secondary hyperparathyroidism, highlighting the importance of considering both clinical efficacy and cost-effectiveness. This knowledge can empower healthcare providers to make informed decisions, navigating the complex landscape of treatment options while balancing clinical outcomes with resource constraints.

Dr.Camel's Conclusion

This study offers a valuable perspective on the economic implications of treating secondary hyperparathyroidism in patients with chronic kidney disease. The research suggests that cinacalcet, a promising oasis in the desert of cost-effective therapies, offers a favorable economic profile compared to vitamin D alone. By considering both clinical efficacy and cost-effectiveness, we can navigate the complex landscape of treatment decisions, ensuring optimal patient care while maximizing resource utilization.

Date :
  1. Date Completed 2010-12-16
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20951487

DOI: Digital Object Identifier

10.1053/j.ajkd.2010.07.012

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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