Paper Details 
Original Abstract of the Article :
Zidovudine and lamivudine (ZDV and 3TC) are long-standing nucleoside analog-reverse transcriptase inhibitors (NRTIs) with extensive clinical experience in a wide spectrum of patients from in utero through childhood and adult ages. The safety profiles of both drugs are well-known and side effects for...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/20953318

データ提供:米国国立医学図書館(NLM)

Combating HIV: The Power of Zidovudine and Lamivudine

HIV infection remains a significant global health concern. This research explores the effectiveness and safety of Zidovudine and lamivudine (ZDV and 3TC), two nucleoside analog-reverse transcriptase inhibitors (NRTIs), in treating HIV infection. The authors provide a comprehensive overview of these drugs, including their safety profiles, efficacy, and potential applications in various patient populations, including children, pregnant women, and those with HIV-associated neurological deficits. They also highlight the role of ZDV-3TC in preventing drug resistance and its potential use in combination therapies.

ZDV and 3TC: A Powerful Duo

The research highlights the effectiveness and safety of ZDV and 3TC as a viable treatment option for HIV infection. While other therapies, such as tenofovir disoproxil fumarate-emtricitabine (TDF-FTC), are often preferred, ZDV-3TC remains a valuable alternative, especially in situations where other options are unavailable or contraindicated. The study also emphasizes the importance of ZDV-3TC in preventing drug resistance and its potential role in combination therapies.

A Light at the End of the Tunnel: Hope for HIV Treatment

This research highlights the importance of continuous innovation and adaptation in developing effective treatments for HIV infection. ZDV and 3TC, while not the only treatment option, remain valuable tools in the fight against HIV. The study also emphasizes the importance of considering individual needs and tailoring treatment strategies to maximize effectiveness and minimize side effects.

Dr.Camel's Conclusion

Just as a camel can traverse vast desert landscapes, researchers are constantly seeking new pathways to effectively combat HIV infection. This research provides a valuable overview of the strengths and limitations of ZDV and 3TC, offering insight into their role in the ongoing fight against this challenging disease.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20953318

DOI: Digital Object Identifier

NIHMS205960

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Languages

English

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