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Study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment in the prevention of depressive relapse/recurrence: the PREVENT trial.

Author: ByfordSarah, ByngRichard, DalgleishTim, EvansAlison, HayesRachel, KesslerDavid, KuykenWillem, LanhamPaul, LewisGlyn, MorantNicola, TaylorRod, WatkinsEdward R

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examines the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for preventing depression relapse compared to continuing medication (maintenance antidepressants). The study aims to determine if MBCT is superior in terms of preventing relapse over 24 months, as well as its impact on other factors like the number of days without depression, remaining symptoms, medication use, other mental and physical health conditions, quality of life, and cost-effectiveness. The study also aims to explore if improvements in mindfulness skills are a key factor in the effectiveness of MBCT.
Paper Details　
Original Abstract of the Article :
Depression is a common and distressing mental health problem that is responsible for significant individual disability and cost to society. Medication and psychological therapies are effective for treating depression and maintenance anti-depressants (m-ADM) can prevent relapse. However, individuals ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972263/

データ提供：米国国立医学図書館（NLM）

Preventing Depression's Recurrence: A Journey Through the Mind's Oasis

[Depression] is a common and distressing mental health condition. It can feel like a relentless desert, leaving individuals feeling lost and parched. This study, known as the PREVENT trial, embarks on a journey to find a more effective oasis – a treatment that can prevent the recurring sandstorms of depressive episodes.

The researchers are investigating the potential of [Mindfulness-based Cognitive Therapy (MBCT)] as a viable alternative to traditional [maintenance anti-depressant treatment]. Imagine MBCT as a calm oasis, offering a safe space for individuals to learn tools for managing their mental well-being.

A More Sustainable Oasis: A Promising Path to Prevention

Previous research has shown that MBCT can [halve the rates of depression recurring] compared to [usual care]. This study aims to confirm these findings, using a [randomized controlled trial] to compare MBCT with [m-ADM] over a [24-month period]. The researchers are hoping to find a more sustainable oasis – a treatment that offers long-term relief from the recurring droughts of depression.

Finding Your Oasis: Seeking Psychological Support

This research highlights the importance of exploring various approaches to managing depression. If you are struggling with depression, remember that you are not alone. Seek help from a qualified mental health professional to find the right oasis for your needs – a treatment that provides the support and tools you need to thrive.

Dr.Camel's Conclusion

This research offers hope for individuals who have experienced the recurring cycles of depression. By exploring the potential of [Mindfulness-based Cognitive Therapy], the PREVENT trial aims to pave a path toward a more sustainable oasis for mental well-being – a path that can lead to a calmer, more fulfilling future.

Date :
  1. Date Completed 2010-12-29
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

20961444

DOI: Digital Object Identifier

PMC2972263

Related Literature

Article Analysis
・Effective treatment of depression
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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