Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomised study over 21 months.

Author: BrismarKerstin, EngvallInga-Lill, HafströmIngiäld, TengstrandBirgitta

Paper Details 
Original Abstract of the Article :
Rheumatoid arthritis (RA) is associated with changes in body composition and bone mineral density (BMD). The purpose of the present study was to evaluate whether anti-TNF treatment in early RA has an impact on body composition and BMD besides that which could be achieved by intensive disease-modifyi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991034/

データ提供:米国国立医学図書館(NLM)

Infliximab: Impact on Body Composition in Early Rheumatoid Arthritis

The field of [rheumatology] is constantly seeking to understand the multifaceted effects of [anti-TNF treatment] on patients with [rheumatoid arthritis]. This study investigates the impact of [infliximab] on [body composition and bone mineral density (BMD)] in individuals with [early rheumatoid arthritis]. Researchers conducted a [randomized study over 21 months] comparing the effects of infliximab to [intensive disease-modifying anti-rheumatic drug (DMARD) combination therapy]. They found that [infliximab therapy increased body fat mass] independently of changes in disease activity and levels of leptin and adiponectin. The study highlighted [the potential for infliximab to influence body composition] in patients with early rheumatoid arthritis.

Infliximab: A New Perspective on Body Composition in Rheumatoid Arthritis

This research provides a new perspective on the effects of [infliximab] on body composition in patients with rheumatoid arthritis. The study's findings demonstrate [the potential for infliximab to increase body fat mass].

Navigating the Shifting Sands of Rheumatoid Arthritis Treatment

Treating rheumatoid arthritis can be like navigating a desert with ever-changing landscapes. This study helps us understand the [impact of infliximab on body composition] and navigate the complex terrain of rheumatoid arthritis treatment.

Dr. Camel's Conclusion

This study offers a glimpse into the multifaceted effects of infliximab on body composition in rheumatoid arthritis. The researchers have illuminated a new aspect of this complex disease, providing valuable insights for clinicians managing patient care.

Date :
  1. Date Completed 2011-03-31
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

20964833

DOI: Digital Object Identifier

PMC2991034

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.