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Original Abstract of the Article :
OBJECTIVES: It is unknown if telbivudine causes muscle damage only in patients with pre-existing muscle pathology. CASE REPORT: A 27 yo male of African origin received telbivudine for hepatitis B during 3 months. Three weeks after initiation of the drug he developed myalgia, and tiredness. Creatine...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998482/
データ提供:米国国立医学図書館(NLM)
Telbivudine Myotoxicity: A Case for Careful Monitoring
The use of medications, like navigating a vast desert, requires careful consideration of potential side effects. In this case report, we delve into the unexpected effects of telbivudine, a medication used for hepatitis B treatment, on muscle health. We encountered a patient who developed muscle pain and fatigue after taking telbivudine. Further investigations revealed a significant increase in creatine kinase levels, indicating muscle damage.
Pre-Existing Muscle Damage: A Vulnerability
Our findings suggest that telbivudine may exacerbate pre-existing muscle damage, leading to accelerated muscle toxicity. It's like adding a heavy load to a camel already burdened by a long journey - the strain can be overwhelming.
Protecting Muscle Health
Therefore, patients taking telbivudine should be closely monitored for signs of muscle problems, and those with pre-existing muscle conditions should avoid this medication altogether. Just as a traveler in the desert conserves water, doctors must carefully consider the potential consequences of medication choices and ensure the safety of their patients.
Dr.Camel's Conclusion
This case report serves as a stark reminder of the importance of vigilant monitoring for drug-related side effects, especially in patients with pre-existing conditions. It highlights the crucial need for close collaboration between doctors and patients to ensure the safe and effective use of medications.
Date :
- Date Completed 2011-01-31
- Date Revised 2021-10-20
Further Info :
Related Literature
English
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