Myotoxicity of telbivudine in pre-existing muscle damage.

Author: AyLeyla, FinstererJosef

Paper Details 
Original Abstract of the Article :
OBJECTIVES: It is unknown if telbivudine causes muscle damage only in patients with pre-existing muscle pathology. CASE REPORT: A 27 yo male of African origin received telbivudine for hepatitis B during 3 months. Three weeks after initiation of the drug he developed myalgia, and tiredness. Creatine...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998482/

データ提供:米国国立医学図書館(NLM)

Telbivudine Myotoxicity: A Case for Careful Monitoring

The use of medications, like navigating a vast desert, requires careful consideration of potential side effects. In this case report, we delve into the unexpected effects of telbivudine, a medication used for hepatitis B treatment, on muscle health. We encountered a patient who developed muscle pain and fatigue after taking telbivudine. Further investigations revealed a significant increase in creatine kinase levels, indicating muscle damage.

Pre-Existing Muscle Damage: A Vulnerability

Our findings suggest that telbivudine may exacerbate pre-existing muscle damage, leading to accelerated muscle toxicity. It's like adding a heavy load to a camel already burdened by a long journey - the strain can be overwhelming.

Protecting Muscle Health

Therefore, patients taking telbivudine should be closely monitored for signs of muscle problems, and those with pre-existing muscle conditions should avoid this medication altogether. Just as a traveler in the desert conserves water, doctors must carefully consider the potential consequences of medication choices and ensure the safety of their patients.

Dr.Camel's Conclusion

This case report serves as a stark reminder of the importance of vigilant monitoring for drug-related side effects, especially in patients with pre-existing conditions. It highlights the crucial need for close collaboration between doctors and patients to ensure the safe and effective use of medications.

Date :
  1. Date Completed 2011-01-31
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21083916

DOI: Digital Object Identifier

PMC2998482

Related Literature

SNS
PICO Info
in preparation
Languages

English

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