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Barbiturate detection in oral fluid, plasma, and urine.
Author: BlumKristen, BuchhalterAugust R, ConeEdward J, FritchDean, KardosKeith, NonnemacherSheena
Original Abstract of the Article :
BACKGROUND: Although current abuse of barbiturates is low compared with other classes of abused drugs, their narrow margin of safety, risk of dependence, and abuse liability remain a health concern. Limited information is available on the disposition of barbiturates in different biologic matrices. ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/FTD.0b013e3182018151
データ提供:米国国立医学図書館(NLM)
The Trail of Barbiturates: A Journey Through the Body
This study delves into the fascinating world of barbiturates, a class of medications known for their sedative and hypnotic effects. While their current abuse is relatively low compared to other drugs, their narrow therapeutic range and potential for dependence remain significant concerns. This study seeks to understand how barbiturates travel through the body, specifically their presence in oral fluid, plasma, and urine. The researchers administered single doses of three different barbiturates to healthy volunteers and tracked their levels in these bodily fluids over time. The results reveal that barbiturates are detectable in all three fluids, providing valuable insights into their elimination patterns.
Following the Tracks of Barbiturates
The research found that barbiturates are readily detectable in oral fluid, plasma, and urine, allowing healthcare providers to monitor their levels in patients. This study provides valuable insights into the pharmacokinetic properties of barbiturates, information that can guide treatment strategies and ensure patient safety.
Understanding the Impact of Barbiturates
The findings underscore the importance of careful barbiturate use due to their potential for side effects, such as dizziness and drowsiness. It's crucial for individuals taking barbiturates to be aware of these potential side effects and to follow their healthcare provider's instructions carefully.
Dr.Camel's Conclusion
This study sheds light on the journey of barbiturates through the body, providing valuable insights into their elimination patterns. Like a desert traveler carefully navigating their way, we must approach barbiturate use with caution and awareness.
Date :
- Date Completed 2011-08-10
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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