Barbiturate detection in oral fluid, plasma, and urine.

Author: BlumKristen, BuchhalterAugust R, ConeEdward J, FritchDean, KardosKeith, NonnemacherSheena

Paper Details 
Original Abstract of the Article :
BACKGROUND: Although current abuse of barbiturates is low compared with other classes of abused drugs, their narrow margin of safety, risk of dependence, and abuse liability remain a health concern. Limited information is available on the disposition of barbiturates in different biologic matrices. ...See full text at original site
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引用元:
https://doi.org/10.1097/FTD.0b013e3182018151

データ提供:米国国立医学図書館(NLM)

The Trail of Barbiturates: A Journey Through the Body

This study delves into the fascinating world of barbiturates, a class of medications known for their sedative and hypnotic effects. While their current abuse is relatively low compared to other drugs, their narrow therapeutic range and potential for dependence remain significant concerns. This study seeks to understand how barbiturates travel through the body, specifically their presence in oral fluid, plasma, and urine. The researchers administered single doses of three different barbiturates to healthy volunteers and tracked their levels in these bodily fluids over time. The results reveal that barbiturates are detectable in all three fluids, providing valuable insights into their elimination patterns.

Following the Tracks of Barbiturates

The research found that barbiturates are readily detectable in oral fluid, plasma, and urine, allowing healthcare providers to monitor their levels in patients. This study provides valuable insights into the pharmacokinetic properties of barbiturates, information that can guide treatment strategies and ensure patient safety.

Understanding the Impact of Barbiturates

The findings underscore the importance of careful barbiturate use due to their potential for side effects, such as dizziness and drowsiness. It's crucial for individuals taking barbiturates to be aware of these potential side effects and to follow their healthcare provider's instructions carefully.

Dr.Camel's Conclusion

This study sheds light on the journey of barbiturates through the body, providing valuable insights into their elimination patterns. Like a desert traveler carefully navigating their way, we must approach barbiturate use with caution and awareness.

Date :
  1. Date Completed 2011-08-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21099741

DOI: Digital Object Identifier

10.1097/FTD.0b013e3182018151

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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