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Opioid antagonists for alcohol dependence.

Author: Hackl-HerrwerthAndrea, LeuchtStefan, RösnerSusanne, SoykaMichael, SrisurapanontManit, VecchiSimona

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review of 50 randomized controlled trials found that naltrexone was effective in reducing heavy drinking and drinking days in patients with alcohol dependence. The review also found that naltrexone was well-tolerated, with gastrointestinal problems and sedative effects being the most common side effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Alcohol dependence belongs to the globally leading health risk factors. Therapeutic success of psychosocial programs for relapse prevention is moderate and could be increased by an adjuvant treatment with the opioid antagonists naltrexone and nalmefene. OBJECTIVES: To determine the effe...See full text at original site
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引用元：
https://doi.org/10.1002/14651858.CD001867.pub3

データ提供：米国国立医学図書館（NLM）

Opioid Antagonists: A Powerful Tool for Alcohol Dependence

The field of [alcohol dependence] research strives to find effective treatments for this complex and challenging condition. This review examined the [effectiveness and tolerability] of [opioid antagonists] in the treatment of [alcohol dependence]. The researchers analyzed data from [50 randomized controlled trials] involving [7793 patients] to determine the impact of [naltrexone and nalmefene] on [drinking-related outcomes].

A Promising Approach to Alcohol Dependence

The review found that [naltrexone] significantly reduced the [risk of heavy drinking] and [decreased drinking days]. While [nalmefene] showed less conclusive results, the overall findings suggest that [opioid antagonists] could be a valuable tool in the treatment of [alcohol dependence]. These results highlight the potential of [opioid antagonists] to help individuals overcome this challenging condition and achieve long-term sobriety.

Navigating the Road to Sobriety

Imagine a desert traveler, facing a difficult journey through treacherous terrain. This review explores the use of [opioid antagonists] as a guide for those seeking to navigate the difficult path to sobriety. The findings suggest that [naltrexone] can help individuals avoid the pitfalls of [heavy drinking] and [alcohol dependence]. This research offers a beacon of hope for those struggling with this debilitating condition, suggesting that recovery is possible with the right support and treatment.

Dr. Camel's Conclusion

This review offers valuable insights into the potential of opioid antagonists for treating alcohol dependence. Naltrexone, in particular, appears to be a promising tool for reducing heavy drinking and increasing the likelihood of achieving sobriety. By harnessing the power of these medications, we can help individuals overcome this challenging condition and embark on a path toward a healthier and more fulfilling life. Just as a camel navigates the desert with resilience and determination, so too can individuals with alcohol dependence find strength and hope with the right support and treatment.

Date :
  1. Date Completed 2011-02-10
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

21154349

DOI: Digital Object Identifier

10.1002/14651858.CD001867.pub3

Related Literature

Article Analysis
・Effective treatment of alcohol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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