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Effect of memantine on resting state default mode network activity in Alzheimer's disease.
Author: AlessandriniFranco, BeltramelloAlberto, CaltagironeCarlo, CanuElisa, CostardiDaniela, CotelliMaria, FrisoniGiovanni B, LorenziMarco, MercuriNicola B, PizziniFrancesca B, RosiniSandra, ZoccatelliGiada
Original Abstract of the Article :
Memantine is an approved symptomatic treatment for moderate to severe Alzheimer's disease that reduces the excitotoxic effects of hyperactive glutamatergic transmission. However, the exact mechanism of the effect of memantine in Alzheimer's disease patients is poorly understood. Importantly, the def...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2165/11586440-000000000-00000
データ提供:米国国立医学図書館(NLM)
Memantine and the Brain's Default Mode Network: A Journey into Alzheimer's Disease
Alzheimer's disease, a devastating neurological condition, affects millions worldwide. This study delves into the role of memantine, a medication used to treat Alzheimer's, in the brain's default mode network (DMN). The DMN is like a bustling desert city, constantly active, playing a crucial role in attention and cognitive function. The study explores how memantine might influence this vital network in Alzheimer's patients.
Memantine: A Potential Oasis in the Desert of Alzheimer's
While memantine is known to reduce the harmful effects of excessive glutamate in the brain, its exact mechanism of action in Alzheimer's disease is still being explored. The researchers are seeking clues like explorers uncovering ancient artifacts in the sands of time. Understanding how memantine interacts with the DMN could pave the way for more effective treatments for Alzheimer's.
A Beacon of Hope in the Alzheimer's Desert
This study offers a glimmer of hope in the vast desert of Alzheimer's research. The DMN is a vital network, and understanding how memantine interacts with it could lead to innovative therapeutic strategies. It's a reminder that even in the most challenging landscapes, new discoveries can emerge, offering pathways to better health and well-being.
Dr. Camel's Conclusion
Alzheimer's disease is a formidable opponent, but researchers are relentlessly searching for solutions. This study, like a lone camel venturing into a seemingly barren desert, explores the potential of memantine to positively influence the brain's default mode network. The journey is ongoing, but the pursuit of understanding and effective treatments for Alzheimer's is vital, bringing hope to those affected and their loved ones.
Date :
- Date Completed 2011-08-15
- Date Revised 2021-10-20
Further Info :
Related Literature
English
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