Challenges in the design and conduct of controlled clinical effectiveness trials in schizophrenia.

Author: , BarnettPaul G, FioreLouis, HuangGrant D, KrystalJohn H, LewRobert, LiangMatthew H, NealCarla, RosenheckRobert A, ThwinSoe Soe, ValleyDanielle, VertreesJulia E

Paper Details 
Original Abstract of the Article :
The introduction of antipsychotic medication has been a major advance in the treatment of schizophrenia and allows millions of people to live outside of institutions. It is generally believed that long-acting intramuscular antipsychotic medication is the most effective approach to increasing medicat...See full text at original site
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引用元:
https://doi.org/10.1177/1740774510392931

データ提供:米国国立医学図書館(NLM)

Challenges in Treating Schizophrenia

The introduction of antipsychotic medications has been a revolutionary breakthrough in the treatment of schizophrenia. It's like finding a new source of water in the desert, allowing millions of people to live fulfilling lives outside of institutions.

This article discusses the complexities of conducting controlled clinical trials for schizophrenia, particularly in the context of long-acting intramuscular antipsychotics. These medications are often considered the gold standard for improving medication adherence and reducing relapses in high-risk patients. However, the research supporting their efficacy is limited, making it difficult to definitively assess their true impact.

The Need for Robust Research in Schizophrenia Treatment

The lack of robust research on long-acting antipsychotics underscores the ongoing need for further investigation in this area. It's like trying to map out a vast desert without a compass – the journey is fraught with uncertainty and requires careful exploration.

Implications for Schizophrenia Treatment and Research

This study highlights the importance of rigorous research in schizophrenia treatment. As we continue to navigate the desert of mental health challenges, we need reliable research to guide us toward more effective treatments and improved outcomes for patients.

Dr. Camel's Conclusion

The search for effective treatments for schizophrenia is a continuous journey, and this research sheds light on the challenges we face. Just as the desert is a demanding environment, so too is the world of mental health. By conducting rigorous research and embracing innovative approaches, we can continue to make progress in understanding and treating this complex condition.

Date :
  1. Date Completed 2011-08-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21270143

DOI: Digital Object Identifier

10.1177/1740774510392931

Related Literature

SNS
PICO Info
in preparation
Languages

English

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