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Schizophrenia: a systematic review of the disease state, current therapeutics and their molecular mechanisms of action.
Author: CapuanoB, CrosbyI T, MaloneD T, ShinJ K
Original Abstract of the Article :
The treatment of schizophrenia, one of the most debilitating mental illnesses, began by the serendipitous discovery of chlorpromazine. Since then, researchers have endeavored to find the cause of the illness but it remains unresolved. As a result, literature on the etiology of schizophrenia is litte...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/092986711795029546
データ提供:米国国立医学図書館(NLM)
Schizophrenia: A Journey Through the Labyrinth of the Mind
This comprehensive review delves into the complex world of [Schizophrenia], a debilitating mental illness that has puzzled researchers for decades. It's like navigating a labyrinth, searching for the key to unlock the mysteries of this condition.
The journey to understand schizophrenia began with the serendipitous discovery of chlorpromazine, a drug that offered relief from the debilitating symptoms. Since then, researchers have tirelessly sought the root cause, but the answer remains elusive. Two prominent hypotheses, however, have stood the test of time: the dopamine and serotonin hypotheses.
This review presents a thorough overview of schizophrenia, summarizing the leading hypotheses, discussing currently available treatments, and exploring promising drug candidates based on preclinical and early clinical trial results. It's like unraveling the threads of a complex tapestry, seeking to understand the interplay of neurotransmitters and their role in this disorder.
The Labyrinth of the Mind: A Glimpse into Schizophrenia Research
This review underscores the challenges and complexities of schizophrenia research. It highlights the ongoing quest to unravel the mechanisms behind this disorder and the potential of new treatments based on promising drug candidates. It's like navigating a labyrinth, with each turn revealing new insights and potential paths to effective treatment.
Hope on the Horizon: Understanding and Treating Schizophrenia
This review offers hope for a future where schizophrenia is better understood and effectively treated. By continuing to delve into the complexities of this disorder and exploring new therapeutic approaches, we can provide better care and support for those affected by this debilitating condition.
Dr. Camel's Conclusion
This review provides a fascinating glimpse into the ongoing quest to understand schizophrenia, a challenging and complex mental illness. The pursuit of knowledge and the development of new treatments offer hope for a future where those affected by this disorder can access better care and support.
Date :
- Date Completed 2011-06-23
- Date Revised 2019-08-23
Further Info :
Related Literature
English
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