An open-label, randomized, multicenter, controlled study of epoetin alfa for the treatment of anemia of chronic kidney disease in the long term care setting.

Author: LangholffWayne, McGowanTracy, PatelMeenakshi, ThimonsDavid G, WinstonJaron L

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the safety and efficacy of epoetin alfa administered in extended-dosing intervals to a target hemoglobin (Hb) level not exceeding 12.0 g/dL for the treatment of anemia in subjects with chronic kidney disease (CKD) not on dialysis. DESIGN: An open-label, randomized, multicente...See full text at original site
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引用元:
https://doi.org/10.1016/j.jamda.2010.09.009

データ提供:米国国立医学図書館(NLM)

Epoetin Alfa: A Refreshing Oasis in the Desert of CKD Anemia

The desert of chronic kidney disease (CKD) often presents the challenge of anemia, a condition that can significantly impact quality of life. This research explores the efficacy and safety of epoetin alfa, a therapeutic oasis, in managing anemia in CKD patients residing in long-term care facilities. The study, a randomized, controlled trial, compared epoetin alfa with standard of care (SOC) in 157 subjects. Epoetin alfa, administered in extended-dosing intervals, demonstrated a significant improvement in hemoglobin levels, a shorter time to response, and fewer blood transfusions compared to SOC. Furthermore, the study highlights the feasibility and effectiveness of extended-dosing intervals, allowing for a more streamlined and convenient treatment approach.

A Beacon of Hope in the Desert of CKD Anemia: Epoetin Alfa

The study's findings offer a refreshing perspective on the management of CKD anemia, demonstrating the effectiveness of epoetin alfa in improving hemoglobin levels, reducing transfusion needs, and streamlining treatment regimens. The positive outcomes observed in the study provide valuable insights for clinicians and patients navigating this challenging condition.

A Sip of Water in the Desert: Extended-Dosing Intervals

The research highlights the potential benefits of extended-dosing intervals, providing a more convenient and manageable treatment approach for patients with CKD anemia. This finding contributes to a more patient-centered approach to care, minimizing the burden of frequent clinic visits and injections. The study underscores the importance of continued research and innovation in finding solutions for CKD anemia, paving the way for a more comfortable and fulfilling life for those living with this condition.

Dr. Camel's Conclusion

The desert of CKD anemia can be a harsh and unforgiving landscape, but this research reveals a refreshing oasis in the form of epoetin alfa. The study's findings highlight the effectiveness of this treatment in improving hemoglobin levels, reducing transfusion needs, and simplifying treatment regimens. While more research is needed to fully understand the long-term implications of epoetin alfa, the study offers a valuable guide for navigating this challenging condition, providing a beacon of hope for those seeking relief from CKD anemia.

Date :
  1. Date Completed 2012-06-20
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

21450214

DOI: Digital Object Identifier

10.1016/j.jamda.2010.09.009

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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