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[Antibiotic prophylaxis in cesarean sections without high risk of infection. Therapeutic trial of cefotetan versus placebo].

Author: BerthetJ, BrunieJ, DoublierC, FauconnierJ, FavierM, MallaretM R, MorelI, RacinetC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cefotetan prophylaxis is effective in reducing postoperative infection rates in caesarean sections without a high risk of infection, leading to reduced hospital stays and lower costs.
Paper Details　
Original Abstract of the Article :
Caesarean sections are performed with an ever increasing frequency, and their morbidity rate due to infection varies between 35 and 40 per cent. The effectiveness of antibiotic prophylaxis has been demonstrated in caesarean sections with a high risk of infection, but few studies have been devoted to...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2147500

データ提供：米国国立医学図書館（NLM）

Antibiotic Prophylaxis in Cesarean Sections: A Balancing Act

Cesarean sections, a common surgical procedure, often come with the risk of postoperative infection. While antibiotics have been shown to be effective in preventing infections in high-risk cases, their role in routine cesarean sections remains a subject of debate. This research delves into the effectiveness of antibiotic prophylaxis in cesarean sections without a high risk of infection, aiming to provide evidence-based insights into this crucial aspect of patient care.

Cefotetan's Positive Impact: Reducing Postoperative Infections

The study, a two-center randomized trial, compared the effectiveness of cefotetan, an antibiotic, with a placebo in women undergoing cesarean sections without a high risk of infection. The results are compelling. The study found that cefotetan significantly reduced the postoperative infection rate, with a 12.5% rate in the treatment group compared to a 26.9% rate in the placebo group. This finding suggests that cefotetan can effectively prevent postoperative infections in this specific patient population.

Safeguarding Maternal Health: A Prudent Approach to Cesarean Sections

The study highlights the potential benefits of antibiotic prophylaxis in cesarean sections, even in cases without a high risk of infection. This can be a valuable tool for protecting maternal health, reducing the risk of complications, and ensuring a smooth recovery. The study emphasizes the importance of a careful assessment of individual risk factors and the potential benefits of antibiotic prophylaxis, particularly in the context of routine cesarean sections.

Dr. Camel's Conclusion

Imagine a caravan traveling through the desert, each member facing the risk of getting lost or injured. Antibiotic prophylaxis in Cesarean sections can be like a trusted guide, providing a shield against potential threats. This research demonstrates how a well-chosen antibiotic can significantly reduce the risk of infection, helping to ensure a safe and healthy journey for mothers after surgery.
Date :
  1. Date Completed 1991-01-14
  2. Date Revised 2016-12-09
Further Info :

Pubmed ID

2147500

DOI: Digital Object Identifier

2147500

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Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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