Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study.

Author: DigiorgioCatherine, GradyJames, HaitzKassie, LapollaWhitney, LuWenzhe, MagelGeorge, MendozaNatalia, TyringStephen

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy of treatment with gabapentin plus valacyclovir hydrochloride for the prevention of postherpetic neuralgia in patients with acute herpes zoster. DESIGN: Uncontrolled, open-label study. SETTING: A private dermatology clinic. PARTICIPANTS: Consecutive immunocompet...See full text at original site
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引用元:
https://doi.org/10.1001/archdermatol.2011.81

データ提供:米国国立医学図書館(NLM)

Combating Postherpetic Neuralgia: A Double Whammy Approach

Herpes zoster, commonly known as shingles, can be a painful and debilitating condition. This study explored the effectiveness of a combined treatment approach involving gabapentin and valacyclovir hydrochloride in preventing postherpetic neuralgia (PHN), a persistent pain that can occur after a shingles infection. Researchers conducted an open-label study involving adults with acute herpes zoster who experienced moderate to severe pain. The findings suggest that this combined therapy significantly reduces the incidence of PHN, indicating its potential benefit for managing the long-term pain associated with shingles.

Preventing Persistent Pain

The study's results highlight the importance of addressing shingles promptly and comprehensively. The combination of gabapentin and valacyclovir hydrochloride proved to be effective in minimizing the risk of developing PHN, which can significantly impact a patient's quality of life. Imagine a camel suffering from a thorn lodged in its foot – treating the wound quickly and effectively can prevent the pain from becoming persistent and debilitating.

Easing the Burden of Shingles

This research underscores the importance of seeking prompt medical attention for shingles. Early diagnosis and treatment with a combination of medications, like gabapentin and valacyclovir hydrochloride, can help prevent long-term complications such as PHN. By addressing the pain and minimizing the risk of persistent discomfort, this treatment approach can empower patients to regain a sense of well-being and live a more comfortable life. Just as a camel needs a skilled handler to guide it through the challenges of the desert, those with shingles can benefit from a healthcare team dedicated to providing comprehensive and timely care.

Dr.Camel's Conclusion

This study shines a light on the importance of proactive treatment for shingles. Combining gabapentin and valacyclovir hydrochloride shows promise in preventing the development of PHN, offering a potential solution to the long-term pain associated with this condition. Remember, just as a camel needs a well-maintained pack saddle to carry its cargo safely, addressing shingles promptly and effectively can help minimize the burden of this challenging condition.

Date :
  1. Date Completed 2011-10-27
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

21482862

DOI: Digital Object Identifier

10.1001/archdermatol.2011.81

Related Literature

SNS
PICO Info
in preparation
Languages

English

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