Short-term effects of morning versus evening dose of hydroxyzine 50 mg on cognition in healthy volunteers.

Hydroxyzine: Cognitive Effects of Morning vs. Evening Doses

Antihistamines are often used to treat allergies, but some can cause drowsiness. This study investigated the cognitive effects of hydroxyzine, a first-generation antihistamine, depending on the time of administration. The researchers compared the effects of evening and morning doses of hydroxyzine on cognitive performance in healthy volunteers.

Hydroxyzine: More Impairment After Morning Doses

The study found that hydroxyzine impaired cognitive performance, particularly on tasks involving divided attention and attention switching. Importantly, impairment was generally larger in magnitude after morning doses compared to evening doses.

Implications for Antihistamine Use

These findings have implications for the use of hydroxyzine, suggesting that it may be more beneficial to take it in the evening to minimize cognitive impairment. Further research is needed to confirm these findings and explore the underlying mechanisms.

Dr. Camel's Conclusion

This study is like a camel caravan crossing the desert, with the timing of hydroxyzine administration affecting the journey's smoothness. The researchers have discovered that morning doses may lead to greater cognitive impairment, highlighting the importance of considering the timing of antihistamine use.