[Design of field studies on vaccines which involves capturing indirect effect].

Author: ChenKun, HuangZheng-qiang, PanJin-ren

Paper Details 
Original Abstract of the Article :
For most variety of vaccines, two types of effects-direct and indirect, can result from immunization programs. Unimmunized individuals in the population that receive immunization program can benefit from the vaccines in addition to the protection from immunization. The classical vaccine trails alloc...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/21518630

データ提供:米国国立医学図書館(NLM)

Measuring the Ripple Effect: Designing Field Studies to Capture Indirect Vaccine Impact

Vaccines are a cornerstone of public health, offering protection against a wide range of diseases. This study delves into the complex world of vaccine research, exploring the concept of indirect effects, which occur when unimmunized individuals benefit from vaccination programs. The study examines different study designs that can account for both direct and indirect effects, leading to a more complete understanding of vaccine efficacy.

Capturing the Indirect Impact of Vaccines

The study's findings highlight the importance of designing field studies that can accurately assess the indirect effects of vaccines. The authors point out that traditional vaccine trials often underestimate the overall impact of vaccination programs by failing to account for indirect effects. The study's insights contribute to a more nuanced understanding of vaccine effectiveness, allowing for better assessment of their true impact on public health.

The Long Reach of Vaccines: Protecting Communities

This study emphasizes the importance of understanding the full impact of vaccines, both on those directly vaccinated and on those who are not. The researchers underscore the importance of designing studies that can capture this crucial indirect effect, leading to more accurate assessments of vaccine effectiveness. The findings suggest that vaccines can have a significant positive impact on entire communities, not just individuals. This research provides a valuable framework for future studies on the impact of vaccination programs, allowing for a more complete understanding of their role in protecting public health.

Dr. Camel's Conclusion

This study reminds us that vaccines can have a far-reaching impact, extending beyond the individual to protect entire communities. The research highlights the importance of understanding both direct and indirect effects of vaccines, allowing for more informed decision-making about vaccination programs. The study is a reminder of the significant role vaccines play in protecting public health and ensuring a healthier future for all.

Date :
  1. Date Completed 2013-09-26
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

21518630

DOI: Digital Object Identifier

21518630

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SNS
PICO Info
in preparation
Languages

Chinese

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