Paper Details

  1. Home
  2. Paper Details

Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.

Author: AkaikeJun, ArakawaTomohiro, ChayamaKazuaki, KamiyaNaohiro, KarinoYoshiyasu, KumadaHiromitsu, KuwataYasuaki, OhmuraTakumi, OzekiItaru, SatoTakahiro, ToyotaJoji, YamadaIchimaro

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the safety, tolerability, and effectiveness of telaprevir monotherapy for 24 weeks in Japanese women with hepatitis C who were difficult to treat with standard therapy. The study found that telaprevir was well tolerated and effective in reducing viral load.
Paper Details　
Original Abstract of the Article :
Anemia is commonly observed as a side effect in a treatment with protease inhibitors combined with peginterferon alpha and ribavirin for hepatitis C virus infection. This study assessed the safety, tolerability, viral kinetics, and selection of variants in telaprevir monotherapy for 24 weeks, and ou...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s00535-011-0411-0

データ提供：米国国立医学図書館（NLM）

Hepatitis C: A Viral Challenge

Hepatitis C virus (HCV) infection, like a desert sandstorm, can wreak havoc on the liver. This research examines the antiviral effects of peginterferon alpha-2b and ribavirin in Japanese patients with HCV infection following a 24-week monotherapy treatment with telaprevir. The study explores the safety, tolerability, viral kinetics, and selection of variants in patients who were difficult to treat with standard therapy. The findings provide insights into the potential role of peginterferon alpha-2b and ribavirin as off-study treatment options for HCV infection.

Combating the Viral Sandstorm

This research examines the effectiveness of peginterferon alpha-2b and ribavirin as off-study treatment options for patients with HCV infection who have difficulty responding to standard therapy. The study provides valuable insights into the safety, tolerability, and antiviral efficacy of these medications in this challenging patient population. The findings offer hope for individuals seeking alternative treatment options to combat HCV infection.

A Path to Viral Clearance

For individuals grappling with HCV infection, finding a path to viral clearance can be a long and arduous journey. This research offers valuable insights into the potential of peginterferon alpha-2b and ribavirin as off-study treatment options, providing hope for patients seeking alternative therapies to achieve viral clearance.

Dr. Camel's Conclusion

This study explores the effectiveness of peginterferon alpha-2b and ribavirin as off-study treatment options for patients with hepatitis C virus infection. The findings suggest that these medications may offer a valuable alternative for individuals who are difficult to treat with standard therapy. Just as a skilled desert traveler utilizes various tools and strategies to navigate the challenging terrain, healthcare professionals need to explore diverse treatment options to combat the complexities of HCV infection.

Date :
  1. Date Completed 2011-11-08
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21556829

DOI: Digital Object Identifier

10.1007/s00535-011-0411-0

Related Literature

Article Analysis
・Effects of telaprevir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.