A randomized trial comparing four Helicobacter pylori eradication regimens: standard triple therapy, ciprofloxacin based triple therapy, quadruple and sequential therapy.

Author: AminianKeyvan, FakhreihSaba, FarsadFaraneh, GhanbariAtefeh, HasheminasabSayed Mohammad

Paper Details 
Original Abstract of the Article :
OBJECTIVE: Helicobacter pylori infection is found in at least 80% of people in developing countries. This randomized controlled trial was performed to evaluate the efficacy of 4 different H. pylori eradication regimens in Iranian patients. METHODS: We enrolled 428 patients referred to Razi hospital...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/21568147

データ提供:米国国立医学図書館(NLM)

Eradicating Helicobacter pylori: A Comparative Study of Four Treatment Regimens

This randomized controlled trial investigates the efficacy of four different treatment regimens for eradicating Helicobacter pylori infection, a common cause of gastritis and peptic ulcers. The study compared standard triple therapy, ciprofloxacin-based triple therapy, quadruple therapy, and sequential therapy, evaluating their effectiveness in Iranian patients. The study found that standard 10-day triple therapy had the highest eradication rate, followed by quadruple therapy. Sequential therapy, however, showed a lower success rate, highlighting the importance of considering individual patient factors when choosing a treatment regimen.

Fighting Helicobacter pylori: A Battle in the Desert of the Stomach

This study delves into the complex world of Helicobacter pylori infection, a microbial foe that can wreak havoc in the stomach lining. The research highlights the importance of selecting effective and well-tolerated treatment regimens to eliminate this persistent bacterium. This study underscores the need for tailored treatment approaches, taking into account individual patient characteristics and optimizing treatment outcomes.

The Importance of Personalized Treatment in Eradicating Helicobacter pylori

This study reminds us that one-size-fits-all approaches are not always effective in treating complex medical conditions like Helicobacter pylori infection. The research highlights the need for individualized treatment strategies, considering factors like patient demographics, geographic location, and susceptibility to antibiotic resistance. This study encourages healthcare providers to carefully assess patient needs and select the most appropriate treatment regimen to achieve optimal outcomes.

Dr. Camel's Conclusion

This randomized controlled trial provides valuable insights into the effectiveness of different treatment regimens for eradicating Helicobacter pylori infection. The study highlights the importance of considering individual patient factors when choosing a treatment regimen, emphasizing the need for tailored approaches to achieve optimal outcomes. This research underscores the complexity of treating Helicobacter pylori infection and encourages continued research into new and improved therapies to effectively eradicate this persistent bacterium.
Date :
  1. Date Completed 2011-06-08
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

21568147

DOI: Digital Object Identifier

21568147

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.