Modulation of metabolic activity of phagocytes by antihistamines.

Author: AmbrožováGabriela, CížMilan, DrábikováKatarína, JančinováViera, KubalaLukáš, LojekAntonin, MačičkováTatiana, MoravcováJana, NosálRadomír, PekarováMichaela, PerečkoTomáš, PečivováJana, VašíčekOndřej

Paper Details 
Original Abstract of the Article :
The purpose of the study was to investigate the effects of H(1)-antihistamines of the 1(st) generation (antazoline, bromadryl, brompheniramine, dithiaden, cyclizine, chlorcyclizine, chlorpheniramine, clemastine) and the 2(nd) generation (acrivastine, ketotifen, and loratadine) on the respiratory bur...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090049/

データ提供:米国国立医学図書館(NLM)

Antihistamines and Phagocytes: A Balancing Act in the Desert of Immunity

The immune system is a complex network of cells and processes that protect us from disease. This study explores the intricate interaction between antihistamines and phagocytes, the cells that engulf and destroy invading pathogens. It aims to understand how different types of antihistamines might affect the ability of phagocytes to fight off infection.

A Balancing Act: Antihistamines and Immune Function

The study found that certain antihistamines, particularly those of the first generation, had a significant inhibitory effect on the activity of phagocytes. This suggests that some antihistamines might compromise the immune system's ability to fight off infection. However, other antihistamines showed less of an effect, suggesting that their use may be preferable in cases of infection.

Navigating the Desert: Choosing the Right Antihistamine

This study highlights the importance of carefully considering the potential effects of antihistamines on immune function. While antihistamines are generally safe and effective for treating allergies, it’s essential to be aware of their potential interactions with the immune system. It's like choosing the right path through the desert—we need to carefully consider the potential pitfalls and obstacles along the way.

Dr. Camel's Conclusion

This research underscores the complex relationship between antihistamines and immune function. It highlights the need for a nuanced understanding of these interactions, especially in the context of infection. It’s a reminder that even in the vast desert of medicine, we must always strive for a balanced and informed approach.

Date :
  1. Date Completed 2011-07-14
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21577279

DOI: Digital Object Identifier

PMC3090049

Related Literature

SNS
PICO Info
in preparation
Languages

English

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