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The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial.

Author: , AungTin, Azuara-BlancoAugusto, BurrJennifer M, ChewPaul, CochranClaire, FosterPaul, FriedmanDavid, LaiJimmy, McDonaldAlison, McPhersonGladys, NolanWinnie, NorrieJohn, QuayyumZahidul, RamsayCraig, ValeLuke

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Glaucoma, a leading cause of blindness, is particularly severe in its angle-closure form. The current standard treatment combines laser surgery and eye drops to lower pressure. This study, EAGLE, investigates whether early removal of the eye's lens, which plays a role in angle-closure glaucoma, could improve outcomes, reduce the need for medications and surgery, and improve quality of life compared to the standard approach.
Paper Details　
Original Abstract of the Article :
Glaucoma is the leading cause of irreversible blindness. Although primary open-angle glaucoma is more common, primary angle-closure glaucoma (PACG) is more likely to result in irreversible blindness. By 2020, 5·3 million people worldwide will be blind because of PACG. The current standard care for P...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121608/

データ提供：米国国立医学図書館（NLM）

Early Lens Extraction for Primary Angle-Closure Glaucoma: A Promising Intervention

Glaucoma is a serious eye condition that can lead to irreversible blindness, and primary angle-closure glaucoma (PACG) is particularly concerning. This study proposes a novel approach to treating PACG: early clear lens extraction. The researchers argue that the lens plays a crucial role in the development of PACG and that removing it early could improve glaucoma control by opening the drainage angle. This study is a randomized controlled trial (EAGLE) designed to evaluate the effectiveness of early lens extraction compared to standard care in terms of patient-reported outcomes, clinical outcomes, and cost-effectiveness.

A New Direction for Glaucoma Treatment

The EAGLE trial aims to determine whether early lens extraction can be a more effective strategy than standard care in treating PACG. The study will assess various aspects, including the impact on visual acuity, the need for medications and further surgeries, and the overall quality of life of patients. The findings of this research could revolutionize the approach to managing PACG and improve the lives of individuals suffering from this condition.

Protecting Vision, Enhancing Quality of Life

The research is a beacon of hope in the fight against glaucoma. By exploring the potential benefits of early lens extraction, this study aims to find ways to preserve vision and enhance the quality of life for patients. It emphasizes the need for continuous innovation in ophthalmology and the importance of developing new treatment options that are both effective and patient-centered.

Dr. Camel's Conclusion

This research is a testament to the innovative spirit of ophthalmology. By exploring the potential of early lens extraction, the study seeks to find new ways to combat glaucoma and protect the precious gift of sight.

Date :
  1. Date Completed 2011-09-16
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

21605352

DOI: Digital Object Identifier

PMC3121608

Related Literature

Article Analysis
・Effective treatment of glaucoma
SNS
PICO Info
in preparation
Languages

English

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