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A watertight acrylic-free titanium recording chamber for electrophysiology in behaving monkeys.

Author: AdamsDaniel L, EconomidesJohn R, HortonJonathan C, JocsonCristina M, ParkerJohn M

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This article describes a titanium recording chamber for neurophysiological recordings in alert monkeys. The chamber fastens to the skull with screws and osseointegrates, making it more durable and less invasive than traditional chambers.
Paper Details　
Original Abstract of the Article :
Neurophysiological recording in alert monkeys requires the creation of a permanent aperture in the skull for repeated insertion of microelectrodes. Most laboratories use polymethyl methacrylate to attach a recording chamber over the skull opening. Here, we describe a titanium chamber that fastens to...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174814/

データ提供：米国国立医学図書館（NLM）

A Watertight Solution: An Acrylic-Free Recording Chamber for Monkeys

Neurophysiological research often involves studying the brain activity of awake monkeys, requiring the implantation of recording chambers. This study explores a new design for a titanium recording chamber that eliminates the need for polymethyl methacrylate, a material that can be associated with complications. The researchers aim to create a more durable and biocompatible chamber for long-term neurophysiological recordings.

The researchers describe a titanium chamber that is secured to the skull with screws, eliminating the need for polymethyl methacrylate. The chamber base osseointegrates with the skull, forming a watertight seal. This innovative design is intended to enhance the longevity and biocompatibility of the recording chamber, minimizing the risk of complications.

A More Durable and Biocompatible Solution

This study offers a promising new approach to designing recording chambers for neurophysiological studies in monkeys. The researchers' innovative design provides a more durable and biocompatible solution, potentially reducing the risk of complications and improving the longevity of the implant.

Advancing Neurophysiological Research

The development of this new chamber design represents a significant advancement in neurophysiological research. It offers a more biocompatible and durable solution for long-term recordings, potentially leading to a better understanding of brain function and improved outcomes for animal subjects.

Dr.Camel's Conclusion

This study demonstrates the ingenuity of researchers in developing new solutions for challenging research needs. The innovative design of the titanium recording chamber offers a more biocompatible and durable solution for long-term neurophysiological studies. It's a testament to the ongoing quest for improved research tools and techniques that can advance our understanding of the complex world of neurophysiology.

Date :
  1. Date Completed 2012-06-26
  2. Date Revised 2023-06-02
Further Info :

Pubmed ID

21676928

DOI: Digital Object Identifier

PMC3174814

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Languages

English

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