Comparison of the novel angiotensin II receptor blocker azilsartan medoxomil vs valsartan by ambulatory blood pressure monitoring.

Author: BakrisGeorge L, CaoCharlie, HandleyAlison, KupferStuart, PerezAlfonso, SicaDomenic, WeberMichael A, WhiteWilliam B

Paper Details 
Original Abstract of the Article :
Azilsartan medoxomil (AZL-M) is a unique angiotensin II receptor blocker (ARB) under development for the treatment of hypertension. To compare this ARB with another in the class, the authors studied the effects of AZL-M and valsartan (VAL) in 984 patients with primary hypertension in a randomized, d...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108745/

データ提供:米国国立医学図書館(NLM)

Comparison of Angiotensin II Receptor Blockers for Hypertension

This research compares the efficacy and safety of two angiotensin II receptor blockers (ARBs), azilsartan medoxomil (AZL-M) and valsartan (VAL), for the treatment of hypertension. The study utilizes ambulatory blood pressure monitoring to assess the effects of these drugs in a large cohort of patients. The findings provide valuable insights into the comparative efficacy and safety of these commonly used antihypertensive agents.

ARBs in the Desert of Hypertension

The study's findings suggest that AZL-M demonstrates superior efficacy compared to VAL in lowering blood pressure. AZL-M achieved greater reductions in both systolic and diastolic blood pressure, both in ambulatory and clinic settings. While both drugs were generally well-tolerated, AZL-M was associated with a slightly higher incidence of reversible changes in serum creatinine.

Hypertension: Navigating the Desert of High Blood Pressure

Hypertension, or high blood pressure, can feel like a relentless desert storm, pushing against the walls of our arteries. This research offers insights into the potential benefits of different ARB medications, like AZL-M and VAL, in managing this condition. The study's findings can help clinicians choose the most effective and safe treatment options for their patients.

Dr. Camel's Conclusion

This research is like a map through the desert of hypertension, providing valuable guidance on the efficacy and safety of different ARB medications. The findings suggest that AZL-M may offer a more effective approach to blood pressure control, offering patients a more comfortable and effective journey through the desert of hypertension.
Date :
  1. Date Completed 2012-01-24
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

21762358

DOI: Digital Object Identifier

PMC8108745

SNS
PICO Info
in preparation
Languages

English

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