The impact of allodynia on the efficacy of almotriptan when given early in migraine: data from the "Act when mild" study.

Author: Díaz-InsaS, FalquésM, ForteaJ, GoadsbyP J, VilaC, ZanchinG

Paper Details 
Original Abstract of the Article :
The objective of this study was to evaluate the impact of allodynia on treatment outcomes in the patients with acute migraine treated in the "Act when Mild" (AwM) study. AwM, a randomized placebo-controlled trial, studied almotriptan 12.5 mg in the early treatment (within 1 hr) of acute migraine whe...See full text at original site
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引用元:
https://doi.org/10.3109/00207454.2011.605191

データ提供:米国国立医学図書館(NLM)

Allodynia and Migraine: Investigating the Impact on Almotriptan Efficacy

Migraine is a debilitating neurological disorder that affects millions worldwide. This study focuses on a key aspect of migraine pain – allodynia, a heightened sensitivity to stimuli that wouldn't normally cause pain. The researchers investigated the impact of allodynia on the effectiveness of almotriptan, a common medication used to treat migraine headaches.

Navigating the Complexities of Migraine Pain

This study delves into the intricate relationship between allodynia and migraine pain, exploring how this heightened sensitivity affects treatment outcomes. The researchers found that while allodynia didn't significantly impact almotriptan's effectiveness in treating mild migraine pain, it did impair the medication's effectiveness in patients experiencing moderate to severe pain. It's like exploring a labyrinthine desert, uncovering hidden connections between different aspects of migraine pain.

Effective Migraine Management: Timing is Key

This research underscores the importance of early intervention in migraine management. Treating migraine headaches when pain is still mild can be more effective, even in the presence of allodynia. It's like finding a shortcut through the desert of migraine pain, reaching the oasis of relief before the pain intensifies. However, further research is needed to fully understand the complex interplay between allodynia, pain intensity, and migraine treatment effectiveness.

Dr.Camel's Conclusion

This study offers valuable insights into the intricacies of migraine pain and treatment. It highlights the importance of early intervention and underscores the need for a more comprehensive understanding of allodynia's role in migraine management. It's like uncovering a new layer in the vast desert of migraine research, leading to a more nuanced approach to treatment.

Date :
  1. Date Completed 2012-08-20
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

21777163

DOI: Digital Object Identifier

10.3109/00207454.2011.605191

Related Literature

SNS
PICO Info
in preparation
Languages

English

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