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Platelet inhibitor therapy. Agents and clinical implications.

Author: ChesebroJ H, FusterV, WebsterM W

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Aspirin is an effective platelet inhibitor that is used to prevent arterial thromboembolic disease.
Paper Details　
Original Abstract of the Article :
Platelets are central to the pathophysiology of an array of vascular disorders. Current platelet-inhibitor drugs reduce platelet aggregation through one of three pathways but do not prevent initial platelet adhesion. The most extensive clinical experience is with aspirin, an irreversible inhibitor o...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2179212

データ提供：米国国立医学図書館（NLM）

Platelet Inhibitors: A Journey Through Thrombosis Prevention

Platelets play a central role in the development of blood clots, making platelet inhibitors crucial for preventing thromboembolic events. This research provides an overview of various platelet inhibitors, their mechanisms of action, and their clinical implications.

Unveiling the Mechanisms: A Spectrum of Platelet Inhibitors

The review explores the different pathways by which platelet inhibitors act, ranging from irreversible inhibition of cyclooxygenase (aspirin) to inhibition of ADP receptors (dipyridamole) and thrombin inhibitors (hirudin). This comprehensive overview highlights the diverse approaches to preventing platelet aggregation and its associated complications.

Protecting Hearts and Brains: Platelet Inhibitors in Action

Imagine a world where heart attacks and strokes are effectively prevented through the use of platelet inhibitors. This research emphasizes the critical role of these medications in preventing arterial thromboembolic disease. The review highlights the efficacy of aspirin in primary and secondary prevention of myocardial infarction, as well as its role in reducing thrombotic complications after coronary angioplasty and revascularization surgery.

Dr. Camel's Conclusion

This review delves into the fascinating world of platelet inhibitors, showcasing their diverse mechanisms of action and their significant contributions to preventing thromboembolic events. The research highlights the importance of these medications in protecting hearts and brains, underscoring their crucial role in cardiovascular health.

Date :
  1. Date Completed 1990-04-26
  2. Date Revised 2007-11-15
Further Info :

Pubmed ID

2179212

DOI: Digital Object Identifier

2179212

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English

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