Clinical experience with lovastatin.

Author: ChremosA N, MantellG E, ShearC L, TobertJ A

Paper Details 
Original Abstract of the Article :
New information on the tolerability of lovastatin has emerged from an ongoing study of long-term therapy; preliminary results from a large, 48-week clinical trial; and spontaneous reports of adverse events observed during prescription use of the drug in the United States. As of June 1989, 744 patien...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9149(90)91251-z

データ提供:米国国立医学図書館(NLM)

Lovastatin: A Look at Its Long-Term Effects

This research examines the long-term safety and efficacy of lovastatin, a medication used to lower cholesterol levels. The authors review data from clinical trials and spontaneous reports to assess the drug's tolerability and potential side effects.

Imagine a caravan journeying across the desert, each camel carrying precious cargo: healthy cholesterol levels. This research investigates whether a medication, lovastatin, can effectively manage this cargo and ensure a smooth and safe journey across the vast desert of our bodies.

Lovastatin's Long-Term Journey

The research found that lovastatin was generally well tolerated in long-term studies. While some adverse events, such as elevated liver enzymes and muscle pain, were observed, their occurrence was relatively low. The study also revealed that the incidence of these events increased with higher doses of lovastatin.

Navigating the Desert of Cholesterol Management

This research highlights the importance of carefully monitoring patients taking lovastatin, especially those receiving higher doses. It emphasizes the need to balance the benefits of cholesterol reduction with the potential for side effects. It's a reminder that the desert of cholesterol management is vast and requires a careful approach to ensure the well-being of our patients.

Dr.Camel's Conclusion

This research provides valuable insights into the long-term safety of lovastatin. It suggests that this medication can be a valuable tool in managing cholesterol levels, but it's important to be aware of the potential risks and to monitor patients carefully. It's like navigating a desert - the journey may have its challenges, but with careful planning and attention to detail, we can reach our destination safely.

Date :
  1. Date Completed 1990-04-19
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

2180268

DOI: Digital Object Identifier

10.1016/0002-9149(90)91251-z

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Languages

English

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