Comparison of calcitriol versus cholecalciferol therapy in addition to oral calcium after total thyroidectomy with central neck lymph node dissection: a prospective randomized study.

Author: ChoeJun-Ho, ChoiJae Hyuck, KimJee Soo, KimJung-Han, KimWan Wook, LeeJeong Eon, LeeSe-Kyung, LimHye In, NamSeok Jin, YangJung-Hyun

Paper Details 
Original Abstract of the Article :
BACKGROUND: The purpose of this study was to determine the effectiveness of oral calcium plus vitamin D supplementation and to compare the effects of cholecalciferol versus calcitriol treatments on postoperative hypocalcemia. METHODS: After total thyroidectomy with central neck dissection, 306 pati...See full text at original site
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引用元:
https://doi.org/10.1002/hed.21619

データ提供:米国国立医学図書館(NLM)

Calcium and Vitamin D: A Vital Duo After Thyroidectomy

Total thyroidectomy, a procedure to remove the entire thyroid gland, can sometimes lead to a decrease in calcium levels, known as hypocalcemia. This study explored the effectiveness of oral calcium and vitamin D supplementation in preventing and managing hypocalcemia after total thyroidectomy with central neck lymph node dissection. Researchers conducted a prospective randomized study to compare the effects of cholecalciferol (vitamin D3) and calcitriol (active form of vitamin D) in addition to oral calcium.

The study found that routine supplementation with oral calcium and vitamin D was beneficial in reducing the incidence of hypocalcemia after thyroidectomy. However, routine supplementation did not completely prevent severe hypocalcemia. The study also revealed that calcitriol was more effective and faster-acting than cholecalciferol when administered after the onset of hypocalcemia. These findings provide valuable insights into the management of hypocalcemia following thyroidectomy, offering a guide through the complex landscape of post-surgical care.

A Balancing Act in the Desert of Thyroid Health

The study highlights the importance of maintaining calcium and vitamin D levels after thyroidectomy, a crucial aspect of post-surgical care. It emphasizes the need for personalized treatment approaches to manage hypocalcemia, taking into account individual patient needs and response to therapy. It's like navigating a delicate balance in a desert environment, where hydration and nutrient intake are essential for survival.

A Vital Oasis for Thyroid Health

The study underscores the importance of vitamin D and calcium supplementation in post-thyroidectomy care. The findings provide valuable guidance for healthcare providers in managing hypocalcemia and improving patient outcomes. It's like discovering a vital oasis in the desert of thyroid health, offering a source of relief and recovery. The study also encourages continued research into the optimal dosages and delivery methods for calcium and vitamin D supplementation to ensure the best possible outcomes for patients.

Dr. Camel's Conclusion

This study emphasizes the importance of calcium and vitamin D supplementation in preventing and managing hypocalcemia after thyroidectomy. The findings provide valuable insights into the role of these essential nutrients in maintaining thyroid health. As a researcher, I'm constantly inspired by the pursuit of knowledge and the development of new therapies to improve patient outcomes.

Date :
  1. Date Completed 2011-12-29
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

21837695

DOI: Digital Object Identifier

10.1002/hed.21619

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English

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