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The effect of high-dose vitamin D on bone mineral density and bone turnover markers in postmenopausal women with low bone mass--a randomized controlled 1-year trial.

Author: AlmåsB, FigenschauY, GrimnesG, JoakimsenR, JordeR, TorjesenP A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

While vitamin D is commonly used to treat osteoporosis, the ideal dose is unclear. This one-year study of 297 women aged 50-80 found that a high dose of vitamin D (6,500 IU/day) did not improve bone density in the hip and spine more than a standard dose (800 IU/day).
Paper Details　
Original Abstract of the Article :
Vitamin D is widely used in osteoporosis treatment, although the optimal dose is not known. This 1-year clinical study among 297 women aged 50-80 years old showed that a vitamin D(3) dose of 6,500 IU/day was not better than the standard dose of 800 IU/day in improving bone mineral density (BMD) in t...See full text at original site
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引用元：
https://doi.org/10.1007/s00198-011-1752-5

データ提供：米国国立医学図書館（NLM）

Vitamin D: A Case for Moderation

This study delves into the intriguing world of vitamin D, a nutrient that plays a crucial role in bone health, like a nourishing oasis in the desert of calcium metabolism. The research investigates the optimal dose of vitamin D for postmenopausal women with low bone mass, exploring whether a high dose of vitamin D offers any added benefits compared to the standard dose. The study, conducted over a year, aimed to assess the impact of these different doses on bone mineral density (BMD) and bone turnover markers, providing valuable insights into the appropriate use of vitamin D for bone health.

Vitamin D: A Balanced Approach to Bone Health

The study suggests that a high dose of vitamin D may not offer significant advantages over the standard dose in improving BMD in postmenopausal women with low bone mass. It's like finding a reliable oasis in a desert, but realizing that a larger oasis doesn't necessarily mean more water. This finding emphasizes the importance of personalized vitamin D recommendations, tailored to individual needs and risk factors. It also highlights the need for further research to determine the optimal dose for various populations and specific bone health conditions.

Navigating the Desert of Bone Health

This research serves as a reminder that there is no one-size-fits-all approach to vitamin D supplementation, especially when it comes to bone health. It's like choosing the right path through a desert landscape, where a single oasis may not be the most ideal destination. Consult with your healthcare provider to discuss the appropriate vitamin D intake for your individual needs, ensuring that you are getting the right amount to support your bone health.

Dr.Camel's Conclusion

This study provides valuable insights into the optimal dose of vitamin D for postmenopausal women with low bone mass, suggesting that a balanced approach is key to maintaining healthy bones. Further research is needed to refine our understanding of the appropriate vitamin D intake for diverse populations and specific bone health conditions.
Date :
  1. Date Completed 2012-03-21
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21909730

DOI: Digital Object Identifier

10.1007/s00198-011-1752-5

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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