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[Influence of intrathecal morphine and buprenorphine on EEG and their analgesic effect].

Author: FukushimaK, NakamuraM, ShimadaM, YonemuraE

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Intrathecal morphine (M) was found to be more effective than intrathecal buprenorphine (B) in providing postoperative analgesia for patients undergoing gynecological surgery. Morphine provided pain relief for 12 hours, while buprenorphine provided pain relief for 6 hours.
Paper Details　
Original Abstract of the Article :
This study was performed on fifty patients undergoing gynecological operations of lower abdomen. Their mean age and body weight were 43 +/- 5yrs and 55 +/- 8kg (mean +/- SD) respectively. All patients were given spinal anesthesia for surgery. Patients were divided into four groups of ten patients at...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2194053

データ提供：米国国立医学図書館（NLM）

Intrathecal Morphine and Buprenorphine: A Journey Through the Desert of Pain Relief

The realm of pain management, much like a vast and unforgiving desert, presents numerous challenges. This study investigates the effects of intrathecal morphine and buprenorphine on electroencephalogram (EEG) readings and their analgesic properties in patients undergoing gynecological surgery. The researchers, like skilled navigators charting a course through a challenging terrain, sought to understand the impact of these drugs on both brain activity and pain perception.

Intrathecal Morphine and Buprenorphine: A Powerful Duo for Pain Relief

The study found that both intrathecal morphine and buprenorphine, like a refreshing oasis in the desert, effectively provided pain relief. The researchers also observed specific EEG changes associated with the administration of these drugs, indicating that they had a distinct impact on brain activity. These findings suggest that both morphine and buprenorphine may offer effective pain management options, but with varying effects on brain activity.

Navigating the Desert of Pain Management

This study highlights the complexity of pain management and the importance of carefully considering the potential effects of different analgesic approaches. The researchers' findings, like a well-worn path through a challenging terrain, emphasize the importance of balancing pain relief with potential side effects, much like a traveler would weigh the benefits of a shortcut against the risks of an unknown route.

Dr.Camel's Conclusion

This study underscores the potential benefits of intrathecal morphine and buprenorphine as effective pain management strategies. The researchers' findings, like a flickering candle in the desert night, offer valuable insights into the complex interplay between analgesics and brain activity. This research serves as a reminder of the importance of careful consideration and a holistic approach to pain management, much like a seasoned traveler navigating the vast and unforgiving desert.

Date :
  1. Date Completed 1990-08-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2194053

DOI: Digital Object Identifier

2194053

SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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