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A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. The Hepatitis Interventional Therapy Group.

Author: , AlbrechtJ, BodenheimerH C, DavisG L, DienstagJ L, FeitD, GibasA, JacobsonI M, KuhnsM, LefkowitchJ, LindsayK, MeschievitzC, O'BrienC, PayneJ, PerrilloR P, SamplinerR, SanghviB, SchiffE R, TamburroC

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This study compared different treatments for chronic hepatitis B, including interferon alone and in combination with prednisone, to a placebo and no treatment.
Paper Details　
Original Abstract of the Article :
Chronic hepatitis B is a common and often progressive liver disorder for which there is no accepted therapy. To assess the efficacy of treatment with interferon, we randomly assigned patients with chronic hepatitis B to one of the following regimens: prednisone for 6 weeks followed by 5 million unit...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199008023230503

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1990-08-15
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

2195346

DOI: Digital Object Identifier

10.1056/NEJM199008023230503

SNS
PICO Info
in preparation
Languages

English

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