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Side effects of methylphenidate in children with attention deficit hyperactivity disorder: a systemic, placebo-controlled evaluation.

Author: BarkleyR A, EdelbrockC S, McMurrayM B, RobbinsK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Methylphenidate was found to be an effective treatment for attention deficit hyperactivity disorder (ADHD) in children, with few, generally mild side effects. The most common side effects reported by parents were decreased appetite, insomnia, stomachaches, and headaches.
Paper Details　
Original Abstract of the Article :
The frequency and severity of 17 side effects presumably associated with stimulant medication were assessed during a rigorous, triple-blind, placebo-controlled, crossover evaluation of methylphenidate, 0.3 and 0.5 mg/kg twice a day, in 83 children with attention deficit hyperactivity disorder. Side ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2196520

データ提供：米国国立医学図書館（NLM）

Exploring the Side Effects of Methylphenidate in Children with ADHD

Dr. Camel, your guide through the sometimes turbulent waters of pediatric medicine, is here to discuss the side effects of methylphenidate, a medication often prescribed for children with ADHD.

The authors conducted a comprehensive, triple-blind, placebo-controlled study to assess the side effects of methylphenidate in children with ADHD. Think of it as meticulously examining the landscape of a desert, carefully observing every detail.

A Closer Look at the Desert of Side Effects

The study found that while some side effects were reported, they were generally mild and less frequent than previously thought. Only a small percentage of children experienced side effects severe enough to require discontinuation of the medication. The authors found that side effects such as decreased appetite, insomnia, stomachaches, and headaches were more frequent during medication periods, but the severity of these side effects remained relatively mild. This is like finding a gentle breeze in a desert storm, providing some comfort and reassurance.

Health Implications and Practical Applications

This study provides valuable information for parents and healthcare providers regarding the side effects of methylphenidate in children with ADHD. It's important to discuss any potential side effects with your doctor and weigh them against the benefits of medication.

Dr. Camel's Conclusion

The desert of ADHD can be challenging to navigate, but this study provides a valuable oasis of information. While some side effects may be present, they are generally mild, and the benefits of medication can outweigh the risks for many children.
Date :
  1. Date Completed 1990-08-23
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

2196520

DOI: Digital Object Identifier

2196520

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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