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A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine 2% cream in tinea cruris.

Author: AvakianEdward, FleischerAlan B, HardasBhushan, OlayinkaBabajide, PappertEric J, ParishJennifer L, ParishLawrence Charles, PlaumStefan, RouthHirak B

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the efficacy and safety of naftifine HCl 2% cream in the treatment of tinea cruris, a fungal infection. The study found that naftifine HCl 2% cream was effective in treating tinea cruris and was well tolerated.
Paper Details　
Original Abstract of the Article :
Naftifine HCl 2% cream (NAFT-2%) is a topical allylamine antifungal preparation under development in the U.S. The objective of this randomized, double-blind, vehicle-controlled study was to evaluate the efficacy and safety of a two-week course of once-daily NAFT-2% vs. vehicle in the treatment of Ti...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/21968664

データ提供：米国国立医学図書館（NLM）

Evaluating the Efficacy and Safety of Naftifine 2% Cream in Tinea Cruris

This research dives deep into the world of dermatology, focusing on the effectiveness and safety of a topical antifungal medication, Naftifine HCl 2% cream (NAFT-2%), in treating Tinea cruris, commonly known as 'jock itch'. Think of this like a camel caravan venturing through the desert, searching for the best way to combat a pesky skin condition. The researchers here used a randomized, double-blind, vehicle-controlled study, which is like blindfolding the camels and giving them different treatments to see which one works best without them knowing what they're getting. They found that NAFT-2% cream was effective in clearing up the infection after a two-week treatment period.

A Promising Solution for Jock Itch

This study suggests that NAFT-2% cream could be a valuable tool for treating Tinea cruris, with its efficacy shown to be promising. It's like finding an oasis in the middle of the desert, a welcome relief from a stubborn skin condition.

Keeping Your Skin Healthy and Happy

If you are experiencing symptoms of Tinea cruris, consult with a dermatologist or healthcare professional to determine the best course of treatment for you. Remember, it's always important to seek professional advice and not rely solely on anecdotal information. This study serves as a reminder that even in the vast desert of medical knowledge, there are always new discoveries and solutions waiting to be found.

Dr.Camel's Conclusion

This study is a great example of how research can help us find effective treatments for common skin conditions. The researchers were able to show that NAFT-2% cream is a safe and effective treatment for Tinea cruris, which is great news for anyone who has ever experienced this itchy and uncomfortable condition. I hope this research inspires further exploration of topical antifungal treatments, just like a camel caravan sets off to explore the wonders of the desert.

Date :
  1. Date Completed 2012-02-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

21968664

DOI: Digital Object Identifier

21968664

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・Effects of naftifine topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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